Therapeutic targeting of the DNA damage mediators CHK1 and Wee1 in neuroblastoma

被引：0

作者：

Russell, Mike ^{[1
]}

Levin, Kirill ^{[1
]}

Rader, JulieAnn ^{[1
]}

Toniatti, Carlo ^{[2
]}

Maris, John M. ^{[1
]}

Cole, Kristina A. ^{[1
]}

机构：

[1] Childrens Hosp Philadelphia, Philadelphia, PA 19104 USA

[2] Merck Res Labs, Boston, MA USA

来源：

CANCER RESEARCH | 2012年 / 72卷

关键词：

D O I：

10.1158/1538-7445.AM2012-1436

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

1436

引用

页数：1

共 50 条

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[22] Direct Targeting of the Cell cycle Regulator WEE1 is a Novel Therapeutic Approach for Neuroblastoma [J].

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[25] The blockade of DNA damage response increase the sensitivity of CHK1 inhibitor in neuroblastoma [J].

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[26] Pharmacological inactivation of CHK1 and WEE1 induces mitotic catastrophe in nasopharyngeal carcinoma cells [J].

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[27] Targeting Chk1 [J].

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[28] Targeting the DNA Damage Response for Cancer Therapy by Inhibiting the Kinase Wee1 [J].

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[29] Mechanistic Distinctions between CHK1 and WEE1 Inhibition Guide the Scheduling of Triple Therapy with Gemcitabine [J].

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[30] EVALUATION OF BBB PERMEABLE WEE1 AND CHK1 INHIBITORS IN COMBINATION WITH STANDARD OF CARE FOR THE TREATMENT OF GLIOBLASTOMA [J].

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