Fluidic platform with embedded differential capacitively coupled contactless conductivity detector for micro-object sensing

被引：8

作者：

Loc Quang Do ^{[1
]}

Tung Thanh Bui ^{[2
,3
]}

Ha Thuy Thi Tran ^{[4
]}

Kikuchi, Katsuya ^{[2
]}

Aoyagi, Masahiro ^{[2
]}

Trinh Chu Duc ^{[3
]}

机构：

[1] Vietnam Natl Univ, Hanoi Univ Sci, Radiophys Dept, Fac Phys, 334 Nguyen Trai, Hanoi, Vietnam

[2] Natl Inst Adv Ind Sci & Technol, Integrat Syst Grp 3D, Tsukuba Cent 1,1-1-1 Umezono, Tsukuba, Ibaraki 3058560, Japan

[3] Vietnam Natl Univ, Univ Engn & Technol, MEMs & Microsyst Dept, Fac Elect & Telecommun, Hanoi 144, Hanoi, Vietnam

[4] Posts & Telecommun Inst Technol, Fac Elect Engn, Km10,Nguyen Trai Rd, Hanoi, Vietnam

来源：

INTERNATIONAL JOURNAL OF NANOTECHNOLOGY | 2018年 / 15卷 / 1-3期

关键词：

microfluidic platform; cell detection; capacitive sensing; CAPILLARY-ELECTROPHORESIS; SENSOR; BUBBLE;

D O I：

10.1504/IJNT.2018.089543

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

In this paper, we present a microfluidic platform with differential capacitively coupled contactless conductivity detection ((DCD)-D-4) technique for microparticle detection. The microfluidic platform is formed by bonding PDMS channel to glass substrate. The proposed microfluidic sensor embedded in the microchannel consists of three adjacent electrodes. These electrodes are arranged to form differential coplanar capacitor structures to provide high sensitivity. The differential capacitance is changed when a microsized object crosses the sensing area in the microfluidic channel. This microfluidic system with the novel sensing design based on (DCD)-D-4 technique provides a platform for detection the presence of an object as well as its electrical property.

引用

页码：24 / 38

页数：15

共 28 条

[1]

[Anonymous], MICROSYST TECHNOL

[2] Capacitive sensing of droplets for microfluidic devices based on thermocapillary actuation [J].

Chen, JZ ;

Darhuber, AA ;

Troian, SM ;

Wagner, S .

LAB ON A CHIP, 2004, 4 (05) :473-480

[3]

da Silva JAF, 1998, ANAL CHEM, V70, P4339

[4]

Do QL, 2015, IEEE SENSOR, P1546

[5] A method of water pretreatment to improve the thermal bonding rate of PMMA microfluidic chip [J].

Du, Liqun ;

Chang, Hongling ;

Song, Mancang ;

Liu, Chong .

MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS, 2012, 18 (04) :423-428

[6] Integrated capillary electrophoresis on flexible silicone microdevices: Analysis of DNA restriction fragments and detection of single DNA molecules on microchips [J].

Effenhauser, CS ;

Bruin, GJM ;

Paulus, A ;

Ehrat, M .

ANALYTICAL CHEMISTRY, 1997, 69 (17) :3451-3457

[7] Detection of microdroplet size and speed using capacitive sensors [J].

Elbuken, Caglar ;

Glawdel, Tomasz ;

Chan, Danny ;

Ren, Carolyn L. .

SENSORS AND ACTUATORS A-PHYSICAL, 2011, 171 (02) :55-62

[8] End-to-End Differential Contact less Conductivity Sensor for Microchip Capillary Electrophoresis [J].

Fercher, Georg ;

Haller, Anna ;

Smetana, Walter ;

Vellekoopt, Michael J. .

ANALYTICAL CHEMISTRY, 2010, 82 (08) :3270-3275

[9] HIGH-FREQUENCY CONTACTLESS CONDUCTIVITY DETECTION IN ISOTACHOPHORESIS [J].

GAS, B ;

DEMJANENKO, M ;

VACIK, J .

JOURNAL OF CHROMATOGRAPHY, 1980, 192 (02) :253-257

[10]

Gas B, 2002, ELECTROPHORESIS, V23, P3520, DOI 10.1002/1522-2683(200210)23:20<3520::AID-ELPS3520>3.0.CO

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