7-iodo-3-isopropylamino-4H-1,2,4-benzothiadiazine 1,1-dioxide

被引：5
作者：
Dupont, L [1 ]
Pirotte, B
de Tullio, P
机构：
[1] Univ Liege, Inst Phys B5, Unite Cristallog, B-4000 Liege, Belgium
[2] Univ Liege, Inst Pharm, Lab Chim Pharmaceut, B-4000 Liege, Belgium
来源：
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | 1999年 / 55卷
关键词：
D O I：
10.1107/S0108270199000669
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The title compound, C10H12IN3O2S, belongs to a new family of heterocyclic drugs developed as putative pancreatic B-cell ATP-sensitive potassium-channel openers. The crystal structure is compared with that of 3-isopropylamino-4-methyl-4H-pyrido [4,3-e][1,2,4]thiadiazine 1,1-dioxide and 3-isopropylamino-4H-pyrido[4,3-e] [1,2,4]thiadiazine 1,1-dioxide. The title compound adopts the 4H-tautomeric form, as in the corresponding pyridinic class of compounds.
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页码：1152 / 1154
页数：3
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