Antioxidant properties of nitrocaffeic acids

被引：11

作者：

Grenier, JL ^{[1
]}

Cotelle, N ^{[1
]}

Cotelle, P ^{[1
]}

Catteau, JP ^{[1
]}

机构：

[1] UNIV SCI & TECH LILLE FLANDRES ARTOIS,CHIM PHYS ORGAN LAB,URA CNRS 351,F-59655 VILLENEUVE DASCQ,FRANCE

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1996年 / 6卷 / 04期

关键词：

D O I：

10.1016/0960-894X(96)00048-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A series of nitrodihydroxybenzenes and nitrocaffeic acids were prepared and their hydroxyl radical (OH degrees) and superoxide anion (O-2(-)) scavenging activities and xanthine oxidase inhibition activities were evaluated. 2-Nitrocaffeic acid is the more potent O-2(-) scavenger. 2-(and 5)-Nitrocaffeic acids are the more potent xanthine oxidase inhibitors.

引用

页码：431 / 434

页数：4

共 14 条

[1] INTEREST OF ESR IN DETERMINING THE MECHANISMS OF DRUG TOXICITY - APPLICATION TO THE ANTIANDROGEN NILUTAMIDE
BERSON, A
WOLF, C
CHACHATY, C
FAU, D
PESSAYRE, D
[J]. JOURNAL DE CHIMIE PHYSIQUE ET DE PHYSICO-CHIMIE BIOLOGIQUE, 1994, 91 (11-12) : 1809 - 1819
[2] BIAGLOW JE, 1982, FREE RADICALS CANCER
[3] HYDROXYL RADICAL SCAVENGING ACTIVITY OF SALICYLIC-ACID AND ITS HYDROXYLATED METABOLITES - AN ESR STUDY
CAPELLE, S
PLANCKAERT, B
COTELLE, P
CATTEAU, JP
[J]. JOURNAL DE CHIMIE PHYSIQUE ET DE PHYSICO-CHIMIE BIOLOGIQUE, 1992, 89 (02) : 561 - 566
[4] CAPELLE S, 1994, REDOX REPORT, V1, P131
[5] SCAVENGER AND ANTIOXIDANT PROPERTIES OF 10 SYNTHETIC FLAVONES
COTELLE, N
BERNIER, JL
HENICHART, JP
CATTEAU, JP
GAYDOU, E
WALLET, JC
[J]. FREE RADICAL BIOLOGY AND MEDICINE, 1992, 13 (03) : 211 - 219
[6] COTELLE N, IN PRESS FREE RADIC
[7] AN EPR STUDY OF THE RADICALS ISSUED FROM NITROCATECHOLS AND NITROHYDROQUINONE - A NEW METHOD OF PRODUCTION OF NITROAROMATIC ANION-RADICALS
GRENIER, JL
COTELLE, P
COTELLE, N
CATTEAU, JP
[J]. JOURNAL DE CHIMIE PHYSIQUE ET DE PHYSICO-CHIMIE BIOLOGIQUE, 1995, 92 (01) : 97 - 103
[8] CHEMOTHERAPEUTIC PROPERTIES OF HETEROCYCLIC-COMPOUNDS - MONOCYCLIC COMPOUNDS WITH 5-MEMBERED RINGS
GRUNBERG, E
TITSWORTH, EH
[J]. ANNUAL REVIEW OF MICROBIOLOGY, 1973, 27 : 317 - 346
[9] KEHRMANN F, 1921, HELV CHIM ACTA, V4, P948
[10] SCAVENGING EFFECTS OF DIHYDRIC AND POLYHYDRIC PHENOLS ON SUPEROXIDE ANION RADICALS, STUDIED BY ELECTRON-SPIN-RESONANCE SPECTROMETRY
KITAGAWA, S
FUJISAWA, H
SAKURAI, H
[J]. CHEMICAL & PHARMACEUTICAL BULLETIN, 1992, 40 (02) : 304 - 307

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