Ras farnesyltransferase inhibitors

被引：22
作者：
AyralKaloustian, S
Skotnicki, JS
机构：
[1] Wyeth-Ayerst Research, Pearl River
来源：
ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 31 | 1996年 / 31卷
关键词：
D O I：
10.1016/S0065-7743(08)60457-1
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
[No abstract available]
引用
收藏
页码：171 / 180
页数：10
相关论文
共 80 条
[1]  
AOKI K, 1995, CANCER RES, V55, P3810
[2]   RATIONAL DESIGN OF POTENT CARBOXYLIC-ACID BASED BISUBSTRATE INHIBITORS OF RAS FARNESYL-PROTEIN TRANSFERASE [J].
BHIDE, RS ;
PATEL, DV ;
PATEL, MM ;
ROBINSON, SP ;
HUNIHAN, LW ;
GORDON, EM .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1994, 4 (17) :2107-2112
[3]   Novel tricyclic inhibitors of farnesyl protein transferase - Biochemical characterization and inhibition of Ras modification in transfected Cos cells [J].
Bishop, WR ;
Bond, R ;
Petrin, J ;
Wang, L ;
Patton, R ;
Doll, R ;
Njoroge, G ;
Catino, J ;
Schwartz, J ;
Windsor, W ;
Syto, R ;
Schwartz, J ;
Carr, D ;
James, L ;
Kirschmeier, P .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (51) :30611-30618
[4]  
BOLTON GL, 1994, ANNU REP MED CHEM, V29, P165
[5]  
BOS JL, 1989, CANCER RES, V49, P4682
[6]  
BUSS BE, 1995, CHEM BIOL, V2, P787
[7]   LOCAL CONSTRAINED SHIFTY PSEUDOPEPTIDES INHIBITORS OF RAS-FARNESYL TRANSFERASE [J].
BYK, G ;
DUCHESNE, M ;
PARKER, F ;
LELIEVRE, Y ;
GUITTON, JD ;
CLERC, FF ;
BECQUART, J ;
TOCQUE, B ;
SCHERMAN, D .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1995, 5 (22) :2677-2682
[8]  
CASEY PJ, 1996, IN PRESS J BIOL CHEM, V271
[9]   Phosphorylation of Bcl-2 protein and association with p21(Ras) in Ras-induced apoptosis [J].
Chen, CY ;
Faller, DV .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (05) :2376-2379
[10]   CONSTRAINED ANALOGS OF KCVFM WITH IMPROVED INHIBITORY PROPERTIES AGAINST FARNESYL TRANSFERASE [J].
CLERC, FF ;
GUITTON, JD ;
FROMAGE, N ;
LELIEVRE, Y ;
DUCHESNE, M ;
TOCQUE, B ;
JAMESSURCOUF, E ;
COMMERCON, A ;
BECQUART, J .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1995, 5 (16) :1779-1784
12345678