The Utility of Administrative Data for Surveillance of Comorbidity in Multiple Sclerosis: A Validation Study

被引：59

作者：

Marrie, Ruth Ann ^{[1
,2
]}

Yu, Bo Nancy ^{[2
]}

Leung, Stella ^{[2
]}

Elliott, Lawrence ^{[2
]}

Caetano, Patricia ^{[2
]}

Warren, Sharon ^{[3
]}

Wolfson, Christina ^{[6
,7
]}

Patten, Scott B. ^{[8
]}

Svenson, Lawrence W. ^{[4
,5
,8
]}

Tremlett, Helen ^{[9
]}

Fisk, John ^{[10
,11
]}

Blanchard, James F. ^{[2
]}

机构：

[1] Univ Manitoba, Dept Internal Med, Winnipeg, MB, Canada

[2] Univ Manitoba, Dept Community Hlth Sci, Winnipeg, MB R3T 2N2, Canada

[3] Univ Alberta, Fac Rehabil Med, Edmonton, AB, Canada

[4] Univ Alberta, Sch Publ Hlth, Edmonton, AB, Canada

[5] Alberta Hlth & Wellness, Surveillance & Assessment, Edmonton, AB, Canada

[6] McGill Univ, Dept Epidemiol & Biostat, Montreal, PQ, Canada

[7] McGill Univ, Res Inst, Ctr Hlth, Montreal, PQ, Canada

[8] Univ Calgary, Dept Community Hlth Sci, Calgary, AB, Canada

[9] Univ British Columbia, Dept Med Neurol, Vancouver, BC V5Z 1M9, Canada

[10] Dalhousie Univ, Dept Psychiat, Halifax, NS, Canada

[11] Dalhousie Univ, Dept Med, Halifax, NS, Canada

来源：

NEUROEPIDEMIOLOGY | 2013年 / 40卷 / 02期

基金：

加拿大健康研究院; 加拿大创新基金会;

关键词：

Multiple sclerosis; Administrative data; Validation; Prevalence; Comorbidity inflammatory bowel disease; Irritable bowel syndrome; Migraine; Epilepsy; Lung disease; IRRITABLE-BOWEL-SYNDROME; QUALITY-OF-LIFE; AUTOIMMUNE-DISEASES; RISING PREVALENCE; HEADACHE; ISCHEMIA;

D O I：

10.1159/000343188

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background: Although comorbidity is important in multiple sclerosis (MS), few validated methods for its assessment exist. We validated and applied administrative case definitions for several comorbidities in MS. Methods: Using provincial administrative data we identified persons with MS and a matched general population cohort. Case definitions for chronic lung disease (CLD), epilepsy, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS) and migraine were developed using administrative data, and validated against medical records. We applied these definitions to estimate the age-standardized prevalence of these comorbidities in the MS and matched cohorts. Results: Versus medical records, administrative case definitions showed moderate agreement for CLD (kappa = 0.41), migraine (kappa = 0.51), and epilepsy (kappa = 0.44), fair agreement for IBS (kappa = 0.36) and could not be calculated for IBD (small sample size). The 2005 prevalence of CLD was similar in the MS (15.6%) and general populations (14.4%). The prevalence of the remaining comorbidities was higher in the MS than the general populations: epilepsy (4.12 vs. 1.12%), IBD (0.78 vs. 0.65%), IBS (12.2 vs. 6.80%) and migraine (23.0 vs. 16.5%). Conclusions: Administrative data are valid for tracking CLD, epilepsy, and migraine in MS. The prevalence of epilepsy, IBD, IBS and migraine is increased in MS versus the general population. Copyright (C) 2012 S. Karger AG, Basel

引用

页码：85 / 92

页数：8

共 37 条

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