Synthesis of Azepine Derivatives by Rhodium-Catalyzed Tandem 2,3-Rearrangement/Heterocyclization

被引：73

作者：

Nakamura, Itaru ^{[1
]}

Okamoto, Masashi ^{[2
]}

Sato, Yoshinori ^{[2
]}

Terada, Masahiro ^{[1
]}

机构：

[1] Tohoku Univ, Grad Sch Sci, Res & Analyt Ctr Giant Mol, Sendai, Miyagi 9808578, Japan

[2] Tohoku Univ, Grad Sch Sci, Dept Chem, Sendai, Miyagi 9808578, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2012年 / 51卷 / 43期

关键词：

alkynes; nitrogen heterocycles; rearrangement; rhodium; ring expansion; INTERMOLECULAR 4+2 CYCLOADDITION; CYCLOPROPYL IMINES; 1ST; VINYLALLENE; VINYLCYCLOPROPANES; TRANSFORMATION; NITROGEN; ALKYNES;

D O I：

10.1002/anie.201205285

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Easy to N-cycle: The efficient synthesis of azepine derivatives was achieved by Rh-catalyzed tandem 2,3-rearrangement involving the heterocyclization of N-allenylnitrone intermediates (see scheme; cod=1,5-cyclooctadiene, tppms=sodium diphenylphosphinobenzene-3-sulfonate). Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：10816 / 10819

页数：4

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