Choroid plexus cysts analyzed using diffusion-weighted imaging with short diffusion-time

被引：13

作者：

Maekawa, Tomoko ^{[1
,2
,3
]}

Hori, Masaaki ^{[1
]}

Murata, Katsutoshi ^{[4
]}

Feiweier, Thorsten ^{[5
]}

Andica, Christina ^{[1
]}

Fukunaga, Issei ^{[1
]}

Koshino, Saori ^{[1
,2
,3
]}

Hagiwara, Akifumi ^{[1
,2
,3
]}

Kamiya, Kouhei ^{[1
,2
,3
]}

Kamagata, Koji ^{[1
]}

Wada, Akihiko ^{[1
]}

Abe, Osamu ^{[2
,3
]}

Aoki, Shigeki ^{[1
]}

机构：

[1] Juntendo Univ, Sch Med, Dept Radiol, Bunkyo Ku, 2-1-1 Hongo, Tokyo 1138421, Japan

[2] Univ Tokyo, Grad Sch Med, Dept Radiol, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1138655, Japan

[3] Univ Tokyo, Fac Med, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1138655, Japan

[4] Siemens Healthcare Japan KK, Shinagawa Ku, Gate City Osaki West Tower,11-1 Osaki 1 Chome, Tokyo 1418644, Japan

[5] Siemens Healthcare GmbH, Henkestr 127, D-91052 Erlangen, Germany

来源：

MAGNETIC RESONANCE IMAGING | 2019年 / 57卷

关键词：

Diffusion-weighted imaging; Oscillating gradient spin-echo; OGSE; Restricted diffusion; Choroid plexus cysts; Diffusion time; LATERAL VENTRICLES; WATER DIFFUSION; MRI; QUANTIFICATION; BRAIN; AXON;

D O I：

10.1016/j.mri.2018.12.010

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Introduction: Oscillating gradient spin-echo (OGSE) sequences can shorten diffusion times by replacing the long-lasting diffusion-sensitizing gradients used in pulsed gradient spin-echo (PGSE) methods with rapidly oscillating gradients. To obtain information regarding the internal structure of choroid plexus cysts that appear hyper-intense on diffusion-weighted imaging (DWI), we investigated the apparent diffusion coefficient (ADC) values acquired with a shorter diffusion time using an OGSE sequence. Material and methods: Twenty-seven patients with choroid plexus cysts were scanned using a 3 T magnetic resonance scanner. DWI was performed with both OGSE and PGSE, with effective diffusion times (Delta(eff)) of 6.5 and 35.2 ms, respectively. ADC values for choroid plexus cysts, white matter (WM), and cerebrospinal fluid (CSF) were measured. The ADC values obtained with the shorter and longer diffusion times were compared using the Wilcoxon signed-rank test. P < .05 was considered significant. Results: The ADC values of choroid plexus cysts and WM were significantly higher at the Delta(eff) of 6.5 ms on OGSE than with the Delta(eff) of 35.2 ms on PGSE. The ADC values of CSF were significantly lower at the Delta(eff) of 6.5 ms on OGSE than with the Delta(eff) of 35.2 ms on PGSE. The ADC values of choroid plexus cysts were lower than the ADC values of CSF with Delta(eff) of 35.2 and 6.5 ms. Conclusions: The dependence of ADC values on the diffusion time in choroid plexus cysts suggested spatially restricted diffusion. In measurements obtained with short diffusion times, the lower ADC values for choroid plexus cysts in comparison with the CSF indicated the presence of spatially restricted diffusion and increased cyst viscosity.

引用

页码：323 / 327

页数：5

共 30 条

[1] Probing mouse brain microstructure using oscillating gradient diffusion MRI [J].