Terpenoids, flavonoids and other constituents of Eupatorium betonicaeforme (Asteraceae)

A new acylated kaurene diterpene, characterized as 15 alpha-decanoyloxy-kaur-16-en-19-oic acid, along with nine known compounds: pentacosanoic acid, 24 alpha-ethyl-5 alpha-cholesta-7,22E-dien-3 beta-ol, 15 alpha-hydroxy-kaur-16-en-19-oic acid, 8 beta-angeloyloxy-9 beta, 10 beta-dihydroxy-1-oxo-germacra-4E, 11(13)dien-12,6 alpha-olide, 3 alpha-hydroxyeicosan-1,5 beta-olide, taraxasteryl acetate, 7-O-methylkaempferol, kaempferol, and nepetin were isolated from the flowers of Eupatorium betonicaeforme (Asteraceae). In addition, from the aerial parts were isolated taraxasteryl acetate and alpha- and beta-amyrin, while the mixture of beta-sitosterol and stigmasterol, and 6-acetyl-2,2-dimethylchroman-4-one were isolated from the roots. The structure elucidation of all compounds was performed by spectroscopic analysis and comparison with published data from literature.