Maturity Onset Diabetes of the Young and Generalized Stage III Grade C Periodontitis: A Case Report

Introduction: Maturity onset diabetes of the young (MODY) is a rare form of diabetes mellitus resulting from single nucleotide polymorphisms. There is a lack of evidence describing their periodontal condition and the management of these patients. The objective of this case report is to present the 6-month outcomes following non-surgical periodontal treatment of a patient diagnosed with MODY 5, the Renal Cyst and Diabetes Syndrome. Case Presentation: This case report describes the periodontal presentation and non-surgical management of a 21-year-old patient, diagnosed with hyperglycemia (HbA1c >14%) and stage 4 chronic kidney disease. She presented with generalized severe chronic periodontitis and multiple periodontal abscesses. She was treated with quadrant debridement with adjunctive systemic amoxicillin and metronidazole and 0.2% chlorhexidine mouth rinse. Significant improvement was observed after treatment, remaining stable 6-month post-treatment, with only two sites with probing depths >= 5 mm. This was consistent with a reduction of the periodontal inflamed surface area from 3165 to 500 mm(2). HbA1c was also reduced to 8.7% 6 months after treatment. Conclusions: MODY patients presenting with periodontitis can be successfully treated non-surgically, concurrent with diabetic management.