B(C6F5)3-catalyzed transfer hydrogenations of imines with Hantzsch esters

被引：19
作者：
Wang, Qiaotian [1 ,2 ]
Chen, Jingjing [1 ,2 ]
Feng, Xiangqing [1 ,2 ]
Du, Haifeng [1 ,2 ]
机构：
[1] Chinese Acad Sci, Inst Chem, CAS Key Lab Mol Recognit & Funct, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2018年 / 16卷 / 09期
基金：
中国国家自然科学基金;
关键词：
METAL-FREE HYDROGENATION; FRUSTRATED LEWIS PAIRS; HIGHLY ENANTIOSELECTIVE HYDROGENATION; ASYMMETRIC TRANSFER HYDROGENATION; CATALYZED TRANSFER HYDROGENATION; MOLECULAR TWEEZERS; DIHYDROGEN; CYCLOHEXA-1,4-DIENES; REDUCTION; BIS(PENTAFLUOROPHENYL)BORANE;
D O I：
10.1039/c8ob00023a
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Highly efficient transfer hydrogenations of imines were realized with as low as 0.1 mol% of B(C6F5)(3) by using Hantzsch esters as a hydrogen source, furnishing a variety of amines in 80-99% yields. For the asymmetric transfer hydrogenations, up to 38% ee was obtained with chiral diene-derived boron Lewis acids.
引用
收藏
页码：1448 / 1451
页数：4
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