Tetrahydroazepines with an annulated five-membered heteroaromatic ring

被引：2

作者：

Danyliuk, Ivanna Yu ^{[1
]}

Vovk, Mykhailo V. ^{[1
]}

机构：

[1] Natl Acad Sci Ukraine, Inst Organ Chem, 5 Akad Kukhara St, UA-02094 Kiev, Ukraine

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2022年 / 58卷 / 11期

关键词：

ENANTIOSELECTIVE SYNTHESIS; INTRAMOLECULAR CYCLIZATION; RECEPTOR ANTAGONIST; KINASE INHIBITORS; DERIVATIVES; POTENT; DISCOVERY; ANALOGS; DESIGN; HYMENIALDISINE;

D O I：

10.1007/s10593-022-03131-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The review summarizes and analyzes the literature data on the synthetic design of promising biologically active hydrogenated furo-, thieno-, pyrrolo-, and azoloazepine systems. The information is systematized according to the principle of prevalence and significance of the employed synthetic methods: annulation of an azepine ring to a five-membered heteroaromatic ring, annulation of a five-membered heteroaromatic ring to an azepine ring, ring expansion reactions of hetaro-annulated cyclohexanones and piperidines. The bibliography of the review contains 94 sources published in 2000-2022.

引用

页码：567 / 581

页数：15

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