Clinical Trial Evidence for Treatment of Depression in Heart Failure

被引：10

作者：

Echols, Melvin R. ^{[1
]}

Jiang, Wei ^{[2
,3
]}

机构：

[1] Duke Univ, Med Ctr, Duke Clin Res Inst, Dept Internal Med, Durham, NC 27710 USA

[2] Duke Univ, Med Ctr, Dept Psychiat & Behav Sci, Durham, NC 27710 USA

[3] Duke Univ, Med Ctr, Dept Internal Med, Durham, NC 27710 USA

来源：

HEART FAILURE CLINICS | 2011年 / 7卷 / 01期

关键词：

Depression; Heart failure; Depression treatment; MAJOR DEPRESSION; DOUBLE-BLIND; MORTALITY; PLACEBO; DISEASE; IMIPRAMINE; MORBIDITY; BUPROPION; SAFETY; RISK;

D O I：

10.1016/j.hfc.2010.08.004

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Depression is an important disease state that requires a significant amount of time and resources for proper management. The presence of depression in patients with cardiovascular disease has been strongly associated with detrimental effects in terms of morbidity and mortality. Little is known about the management of depression in heart failure patients, although several investigators continue to pursue optimal treatment strategies for depression in this population. While limited, the prospective clinical trial data evaluating interventions for depression management in patients with heart failure continue to produce promising findings for progressive and improved management of both depression and heart failure.

引用

页码：81 / +

页数：9

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