The Resident-intruder Paradigm: A Standardized Test for Aggression, Violence and Social Stress

被引：276

作者：

Koolhaas, Jaap M. ^{[1
]}

Coppens, Caroline M. ^{[1
]}

de Boer, Sietse F. ^{[1
]}

Buwalda, Bauke ^{[1
]}

Meerlo, Peter ^{[1
]}

Timmermans, Paul J. A. ^{[2
]}

机构：

[1] Univ Groningen, Dept Behav Physiol, Ctr Behav & Neurosci, NL-9700 AB Groningen, Netherlands

[2] Radboud Univ Nijmegen, NL-6525 ED Nijmegen, Netherlands

来源：

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS | 2013年 / 77期

关键词：

Behavior; Issue; 77; Neuroscience; Medicine; Anatomy; Physiology; Genetics; Basic Protocols; Psychology; offensive aggression; defensive behavior; aggressive behavior; pathological; violence; social stress; rat; Wistar rat; animal model;

D O I：

10.3791/4367

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

This video publication explains in detail the experimental protocol of the resident-intruder paradigm in rats. This test is a standardized method to measure offensive aggression and defensive behavior in a semi natural setting. The most important behavioral elements performed by the resident and the intruder are demonstrated in the video and illustrated using artistic drawings. The use of the resident intruder paradigm for acute and chronic social stress experiments is explained as well. Finally, some brief tests and criteria are presented to distinguish aggression from its more violent and pathological forms.

引用

页数：7

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