Nutrition During Pregnancy, Lactation and Early Childhood and its Implications for Maternal and Long-Term Child Health: The Early Nutrition Project Recommendations

被引:249
作者
Koletzko, Berthold [1 ]
Godfrey, K. M. [2 ,3 ,4 ]
Poston, Lucilla [5 ]
Szajewska, Hania [6 ]
van Goudoever, Johannes B. [7 ]
de Waard, Marita [7 ]
Brands, Brigitte [1 ]
Grivell, Rosalie M. [8 ]
Deussen, Andrea R. [8 ]
Dodd, Jodie M. [8 ]
Patro-Golab, Bernadeta [6 ]
Zalewski, Bartlomiej M. [6 ]
Alberdi, G. [9 ]
Buonocore, G. [10 ]
Campoy, C. [11 ]
Demmelmair, H. [12 ]
Desoye, G. [13 ]
Diaz Gomez, M. [14 ]
Escribano, J. [15 ]
Geraghty, A. [9 ]
Gil, A. [16 ,31 ]
Hanson, M. [17 ]
Inskip, H. M. [2 ,3 ,4 ,9 ]
Larque, E. [9 ,18 ]
Lassel, T. [19 ]
Luque, V [15 ]
Mader, S. [20 ]
Manios, Y. [21 ]
Mearin, L. M. [22 ]
Oddy, W. H. [23 ]
Reynolds, R. M. [24 ]
Rueda, R. [25 ]
Sherry, C. [26 ]
Socha, P. [27 ]
Taylor, P. [28 ]
Van der Beek, E. M. [19 ,30 ]
Weber, M. [12 ]
Crespo-Escobar, P. [29 ]
Gutser, M. [12 ]
Kouwenhoven, S. M. P. [32 ]
Calvo-Lerma, J. [29 ]
Veldhorst, M. [33 ]
机构
[1] Ludwig Maximilians Univ Munchen, Med Ctr LMU Munich, Dr von Hauner Childrens Hosp, LMU, Munich, Germany
[2] Univ Southampton, MRC Lifecourse Epidemiol Unit, Southampton, Hants, England
[3] Univ Southampton, NIHR Southampton Biomed Res Ctr, Southampton, Hants, England
[4] Univ Hosp Southampton NHS Fdn Trust, Southampton, Hants, England
[5] Kings Coll London, Fac Life Sci & Med, Div Womens Hlth, London, England
[6] Med Univ Warsaw, Dept Paediat, Warsaw, Poland
[7] Vrije Univ Amsterdam, Med Ctr, Dept Pediat, Amsterdam, Netherlands
[8] Univ Adelaide, Robinson Res Inst, Discipline Obstet & Gynaecol, Adelaide, SA, Australia
[9] Univ Coll Dublin, Natl Matern Hosp, Sch Med, UCD Perinatal Res Ctr,Obstet & Gynaecol, Dublin, Ireland
[10] Univ Siena, Dept Mol & Dev Med, Siena, Italy
[11] Univ Granada, Sch Med, Dept Paediat, Granada, Spain
[12] Ludwig Maximilians Univ Munchen, LMU, Dr von Hauner Childrens Hosp, Med Ctr LMU Munich, Munich, Germany
[13] Med Univ Graz, Dept Obstet & Gynecol, Graz, Austria
[14] Univ La Laguna, CIBI, CAN, Canary Isl, Spain
[15] Univ Rovira & Virgili, Paediat Res Unit, Reus, Spain
[16] Univ Granada, Inst Nutr & Food Technol Ctr Biomed Res, Dept Biochem & Mol Biol 2, Granada, Spain
[17] Univ Hosp Southampton NHS Fdn Trust UHSFT, NIHR Southampton Biomed Res Ctr, Fac Med, Human Dev & Hlth Acad Unit, Southampton, Hants, England
[18] Univ Murcia, Fac Biol, Dept Physiol, Campus Mare Nostrum, Murcia, Spain
[19] Danone Nutricia Early Life Nutr, Nutricia Res, Utrecht, Netherlands
[20] European Fdn Care Newborn Infants, Munich, Germany
[21] Harokopio Univ Athens, Dept Nutr & Dietet, Athens, Greece
[22] Leiden Univ, Med Ctr, Dept Pediat, Leiden, Netherlands
[23] Univ Tasmania, Menzies Inst Med Res, Hobart, Tas, Australia
[24] Univ Edinburgh, Queens Med Res Inst, British Heart Fdn Ctr Cardiovasc Sci, Endocrinol Unit, Edinburgh, Midlothian, Scotland
[25] Abbott Nutr Res & Dev, Granada, Spain
[26] Abbott Nutr Sci & Med Affairs, Columbus, OH USA
[27] Childrens Mem Hlth Inst, Warsaw, Poland
[28] Kings Coll London, Fac Life Sci & Med, Div Womens Hlth, London, England
[29] La Fe Univ Hosp, Dept Pediat Gastroenterol, Valencia, Spain
[30] Univ Med Ctr Groningen, Dept Pediat, Groningen, Netherlands
[31] Iberoamer Nutr Fdn, Granada, Spain
[32] Vrije Univ Amsterdam, Med Ctr, Dept Pediat, Amsterdam, Netherlands
[33] Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands
基金
欧洲研究理事会; 欧盟第七框架计划; 澳大利亚国家健康与医学研究理事会;
关键词
Early nutrition; Lifestyle; Preconception; Pregnancy; Breastfeeding; Infancy; Early childhood; Obesity; Child health; Recommendations; Micronutrients; Metabolic programming; Developmental programming; GESTATIONAL WEIGHT-GAIN; VITAMIN-D DEFICIENCY; BODY-MASS INDEX; PERICONCEPTIONAL FOLIC-ACID; FORMULA-FED INFANTS; BREAST-FED INFANTS; AGE FOLLOW-UP; PROTEIN-INTAKE; YOUNG-CHILDREN; LIFE-STYLE;
D O I
10.1159/000496471
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: A considerable body of evidence accumulated especially during the last decade, demonstrating that early nutrition and lifestyle have long-term effects on later health and disease ("developmental or metabolic programming"). Methods: Researchers involved in the European Union funded international EarlyNutrition research project consolidated the scientific evidence base and existing recommendations to formulate consensus recommendations on nutrition and lifestyle before and during pregnancy, during infancy and early childhood that take long-term health impact into account. Systematic reviews were performed on published dietary guidelines, standards and recommendations, with special attention to long-term health consequences. In addition, systematic reviews of published systematic reviews on nutritional interventions or exposures in pregnancy and in infants and young children aged up to 3 years that describe effects on subsequent overweight, obesity and body composition were performed. Experts developed consensus recommendations incorporating the wide-ranging expertise from additional 33 stakeholders. Findings: Most current recommendations for pregnant women, particularly obese women, and for young children do not take long-term health consequences of early nutrition into account, although the available evidence for relevant consequences of lifestyle, diet and growth patterns in early life on later health and disease risk is strong. Interpretation: We present updated recommendations for optimized nutrition before and during pregnancy, during lactation, infancy and toddlerhood, with special reference to later health outcomes. These recommendations are developed for affluent populations, such as women and children in Europe, and should contribute to the primary prevention of obesity and associated non-communicable diseases. (c) 2019 S. Karger AG, Basel
引用
收藏
页码:93 / 106
页数:14
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