Synthesis and aminolysis of polysaccharide carbonates

被引：44

作者：

Elschner, Thomas ^{[1
]}

Ganske, Kristin ^{[1
]}

Heinze, Thomas ^{[1
,2
]}

机构：

[1] Univ Jena, Inst Organ Chem & Makromol Chem, Ctr Excellence Polysaccharide Res, D-07743 Jena, Germany

[2] Abo Akad Univ, Lab Fiber & Cellulose Technol, SF-20500 Turku, Finland

来源：

CELLULOSE | 2013年 / 20卷 / 01期

关键词：

Polysaccharide; Carbonate; Carbamate; Aminolysis; NMR spectroscopy; CHLOROFORMATE ACTIVATION; DELIVERY-SYSTEMS; GENE DELIVERY; DEXTRAN; CELLULOSE; DERIVATIVES; EFFICIENT; FLUOROFORMATES; TRANSFECTION; VECTOR;

D O I：

10.1007/s10570-012-9819-9

中图分类号：

TB3 [工程材料学]; TS [轻工业、手工业、生活服务业];

学科分类号：

0805 ; 080502 ; 0822 ;

摘要：

Well soluble dextran-, cellulose-, starch-, and pullulan aryl carbonates were synthesized applying p-NO2-phenyl chloroformate, phenyl chloroformate, and phenyl fluoroformate. Aminolysis of the products obtained, using aliphatic amines or benzyl amines, yield novel soluble polysaccharide carbamates. The influence of the reaction conditions on the reaction efficiency depending on polysaccharide, reagent, and reaction parameters including temperature was studied. Thus a synthesis strategy was developed for the easy and efficient design of structures of polysaccharide-based materials. The products were characterized by means of NMR-, UV-Vis- and FTIR spectroscopy, elemental analysis, and size exclusion chromatography.

引用

页码：339 / 353

页数：15

共 42 条

[1] REACTION OF DEXTRAN CARBONATE WITH AMINO-ACIDS AND POLYPEPTIDES [J].