Advances in Medical Applications of Additive Manufacturing

被引：78

作者：

Li, Chunxu ^{[1
]}

Pisignano, Dario ^{[2
,3
]}

Zhao, Yu ^{[1
]}

Xue, Jiajia ^{[4
]}

机构：

[1] Chinese Acad Med Sci & Peking Union Med Coll, Peking Union Med Coll Hosp, Dept Orthopaed, Beijing 100730, Peoples R China

[2] CNR, Nanosci Inst, Natl Enterprise Nanosci & Nanotechnol, I-56127 Pisa, Italy

[3] Univ Pisa, Dept Phys, I-56127 Pisa, Italy

[4] Beijing Univ Chem Technol, Beijing Lab Biomed Mat, Beijing 100029, Peoples R China

来源：

ENGINEERING | 2020年 / 6卷 / 11期

基金：

中国国家自然科学基金;

关键词：

Additive manufacturing; Medical applications; Pharmaceutics; Medical implants; Medical devices; 3D; TABLETS; SYSTEM; FABRICATION; MODELS; TECHNOLOGIES; SIMULATION; EDUCATION; DEVICE; LIVER;

D O I：

10.1016/j.eng.2020.02.018

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

In the past few decades, additive manufacturing (AM) has been developed and applied as a cost-effective and versatile technique for the fabrication of geometrically complex objects in the medical industry. In this review, we discuss current advances of AM in medical applications for the generation of pharmaceuticals, medical implants, and medical devices. Oral and transdermal drugs can be fabricated by a variety of AM technologies. Different types of hard and soft clinical implants have also been realized by AM, with the goal of producing tissue-engineered constructs. In addition, medical devices used for diagnostics and treatment of various pathological conditions have been developed. The growing body of research on AM reveals its great potential in medical applications. The goal of this review is to highlight the usefulness and elucidate the current limitations of AM applications in the medical field. (C) 2020 THE AUTHORS. Published by Elsevier LTD on behalf of Chinese Academy of Engineering and Higher Education Press Limited Company.

引用

页码：1222 / 1231

页数：10

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