Catalytic enantioselective reductive desymmetrisation of achiral and meso compounds

被引：38

作者：

Fernandez-Perez, Hector ^{[1
]}

Etayo, Pablo ^{[1
]}

Lao, Joan R. ^{[1
]}

Nunez-Ricoa, Jose L. ^{[1
]}

Vidal-Ferran, Anton ^{[1
,2
]}

机构：

[1] Inst Chem Res Catalonia ICIQ, E-43007 Tarragona, Spain

[2] Catalan Inst Res & Adv Studies ICREA, E-08010 Barcelona, Spain

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 91期

关键词：

RING-OPENING REACTIONS; CHIRAL BUILDING-BLOCKS; ASYMMETRIC HYDROGENATION; CYCLIC ANHYDRIDES; ORGANIC-SYNTHESIS; 2,9-SUBSTITUTED 1,10-PHENANTHROLINES; ENZYMATIC DESYMMETRIZATIONS; BIFUNCTIONAL ADDITION; RUTHENIUM COMPLEXES; OXABICYCLIC ALKENES;

D O I：

10.1039/c3cc45466e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Herein an overview of reductive catalytic enantioselective desymmetrisation of achiral or meso compounds is provided. The most efficient reductive desymmetrisations described in the literature, which involve the reduction of C=O, C=N, C=C and C-halogen bonds, or reductive ring-opening, are summarised. The structural diversity of the valuable highly enantioenriched intermediates prepared by reductive desymmetrisation is highlighted.

引用

页码：10666 / 10675

页数：10

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