Fabrication of Biodegradable Electrospun Poly(L-lactide-co-glycolide) Fibers with Antimicrobial Nanosilver Particles

被引：51

作者：

Xu, Xiaoyi ^{[1
,2
]}

Yang, Qingbiao ^{[3
]}

Bai, Jie ^{[3
]}

Lu, Tiancheng ^{[1
]}

Li, Yuxin ^{[2
]}

Jing, Xiabin ^{[1
]}

机构：

[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China

[2] NE Normal Univ, Inst Genet & Cytol, Minist Educ, Res Ctr Agr & Med Gene Engn, Changchun 130024, Peoples R China

[3] Jilin Univ, Dept Chem, Changchun 130023, Peoples R China

来源：

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY | 2008年 / 8卷 / 10期

关键词：

Nanofibers; Silver Nanoparticles; Antimicrobial; Biodegradable Polymer;

D O I：

10.1166/jnn.2008.1193

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Biodegradable poly(lactide-co-glycolide) (PLGA) antimicrobial nanofibers containing silver nanoparticles were prepared by electrospinning technique. Characterization of the Ag/PLGA nanofiber mats were determined by using SEM, TEM, WAXD and UV-vis spectrum. The antibacterial efficacy of the composites mats made of silver nanoparticles and PLGA fibers was measured. The antimicroorganization efficacy of Ag nanoparticles along with the biodegradability of the PLGA fibers can be combined in practical medical applications.

引用

页码：5066 / 5070

页数：5

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