Porous Substrates for Label-Free Molecular Level Detection of Nonresonant Organic Molecules

被引：194
|
作者：
Ko, Hyunhyub
Chang, Sehoon
Tsukruk, Vladimir V. [1 ]
机构：
[1] Georgia Inst Technol, Sch Mat Sci & Engn, Atlanta, GA 30332 USA
来源：
ACS NANO | 2009年 / 3卷 / 01期
关键词：
surface enhanced Raman scattering (SERS); explosives detection; nanoporous structures; gold nanoparticles; ENHANCED RAMAN-SCATTERING; NANOSPHERE LITHOGRAPHY; GOLD NANOPARTICLES; TRACE DETECTION; SURFACE; SILVER; SPECTROSCOPY; SERS; MONOLAYERS; MEMBRANES;
D O I：
10.1021/nn800569f
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We report on the design of practical surface enhanced Raman scattering (SERS) substrate based upon 3D alumina membranes with cylindrical nanopores chemically modified with polyelectrolyte coating and loaded with gold nanoparticle clusters. These substrates allow for a molecular-level, label-free detection of common plastic explosive materials (TNT, DNT) down to 5-10 zeptograms or 15-30 molecules and a common liquid explosive (HMTD) down to 1 picogram. Such a sensitive detection of organic molecules by utilizing efficient SERS substrates opens the path for affordable and label-free detection of trace amount of practically important chemical compounds.
引用
收藏
页码：181 / 188
页数：8
相关论文
共 50 条
  • [31] Label-free optical biosensing at femtomolar detection limit
    Sansone, Lucia
    Macchia, Eleonora
    Taddei, Chiara
    Torsi, Luisa
    Giordano, Michele
    SENSORS AND ACTUATORS B-CHEMICAL, 2018, 255 : 1097 - 1104
  • [32] Label-free aptamer biosensor for selective detection of thrombin
    Na, Weidan
    Liu, Xiaotong
    Wang, Lei
    Su, Xingguang
    ANALYTICA CHIMICA ACTA, 2015, 899 : 85 - 90
  • [33] Mucin 4 detection with a label-free electrochemical immunosensor
    Hosu, Oana
    Tertis, Mihaela
    Melinte, Gheorghe
    Feier, Bogdan
    Sandulescu, Robert
    Cristea, Cecilia
    ELECTROCHEMISTRY COMMUNICATIONS, 2017, 80 : 39 - 43
  • [34] Label-free detection of glycoproteins by the lectin biosensor down to attomolar level using gold nanoparticles
    Bertok, Tomas
    Sediva, Alena
    Katrlik, Jaroslav
    Gemeiner, Pavol
    Mikula, Milan
    Nosko, Martin
    Tkac, Jan
    TALANTA, 2013, 108 : 11 - 18
  • [35] Label-Free Electrochemical Sensing Platform for the Detection of Protease
    Deng, Dehua
    Shi, Yunfeng
    Feng, Hongmei
    Chen, Qianqian
    Li, Dongxiao
    Liu, Lin
    INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE, 2013, 8 (05): : 6933 - 6940
  • [36] Label-free SERS detection of Salmonella Typhimurium on DNA aptamer modified AgNR substrates
    Chen, Jing
    Park, Bosoon
    Huang, Yao-wen
    Zhao, Yiping
    Kwon, Yongkuk
    JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION, 2017, 11 (04) : 1773 - 1779
  • [37] Label-Free DNA Biosensor Based on SERS Molecular Sentinel on Nanowave Chip
    Hoan Thanh Ngo
    Wang, Hsin-Neng
    Fales, Andrew M.
    Vo-Dinh, Tuan
    ANALYTICAL CHEMISTRY, 2013, 85 (13) : 6378 - 6383
  • [38] Ultra-high frequency piezoelectric aptasensor for the label-free detection of cocaine
    Neves, Miguel A. D.
    Blaszykowski, Christophe
    Bokhari, Sumra
    Thompson, Michael
    BIOSENSORS & BIOELECTRONICS, 2015, 72 : 383 - 392
  • [39] SERS imaging for label-free detection of the phospholipids distribution in hybrid lipid membrane
    Ren Wen
    Liu JiYang
    Guo ShaoJun
    Wang ErKang
    SCIENCE CHINA-CHEMISTRY, 2011, 54 (08) : 1334 - 1341
  • [40] Label-Free Detection of Folate Receptor (+) Cells by Molecular Recognition Mediated Electrochemiluminescence of CdTe Nanoparticles
    Jiang, Hui
    Wang, Xuemei
    ANALYTICAL CHEMISTRY, 2014, 86 (14) : 6872 - 6878
12345