Porous Substrates for Label-Free Molecular Level Detection of Nonresonant Organic Molecules

被引：194
|
作者：
Ko, Hyunhyub
Chang, Sehoon
Tsukruk, Vladimir V. [1 ]
机构：
[1] Georgia Inst Technol, Sch Mat Sci & Engn, Atlanta, GA 30332 USA
来源：
ACS NANO | 2009年 / 3卷 / 01期
关键词：
surface enhanced Raman scattering (SERS); explosives detection; nanoporous structures; gold nanoparticles; ENHANCED RAMAN-SCATTERING; NANOSPHERE LITHOGRAPHY; GOLD NANOPARTICLES; TRACE DETECTION; SURFACE; SILVER; SPECTROSCOPY; SERS; MONOLAYERS; MEMBRANES;
D O I：
10.1021/nn800569f
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We report on the design of practical surface enhanced Raman scattering (SERS) substrate based upon 3D alumina membranes with cylindrical nanopores chemically modified with polyelectrolyte coating and loaded with gold nanoparticle clusters. These substrates allow for a molecular-level, label-free detection of common plastic explosive materials (TNT, DNT) down to 5-10 zeptograms or 15-30 molecules and a common liquid explosive (HMTD) down to 1 picogram. Such a sensitive detection of organic molecules by utilizing efficient SERS substrates opens the path for affordable and label-free detection of trace amount of practically important chemical compounds.
引用
收藏
页码：181 / 188
页数：8
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