High-Flow Nasal Cannula and Aerosolized β Agonists for Rescue Therapy in Children With Bronchiolitis: A Case Series

被引：33

作者：

Morgan, Sherwin E. ^{[1
]}

Mosakowski, Steve ^{[1
]}

Solano, Patti ^{[1
]}

Hall, Jesse B. ^{[2
]}

Tung, Avery ^{[3
]}

机构：

[1] Univ Chicago, Dept Resp Care, Chicago, IL 60637 USA

[2] Univ Chicago, Dept Med, Sect Pulm & Crit Care Med, Chicago, IL 60637 USA

[3] Univ Chicago, Dept Anesthesia & Crit Care, Chicago, IL 60637 USA

来源：

RESPIRATORY CARE | 2015年 / 60卷 / 09期

关键词：

asthma; bronchiolitis; beta agonists; HFNC; high-flow nasal cannula; DRUG-DELIVERY; INFANTS; DIAGNOSIS; SIZE;

D O I：

10.4187/respcare.03996

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Asthma and bronchiolitis are episodic obstructive pulmonary diseases characterized by broncho-constriction, airway wall inflammation, increased mucus production, and air-flow obstruction. We present the cases of 5 infants treated for acute bronchiolitis with respiratory distress using a combination of high-flow nasal cannula oxygen (HFNC) and an Aerogen nebulizer to deliver aerosolized beta-agonist therapy. In all infants, we found that HFNC resulted in a greater heart rate increase than delivery via a facemask. We also found that patients tolerated inhaled therapy better with HFNC than a facemask. (c) 2015 Daedalus Enterprises

引用

页码：E161 / E165

页数：5

共 19 条

[1]

Amirav I, 2002, J NUCL MED, V43, P487

[2] Nasal Versus Oral Aerosol Delivery to the "Lungs" in Infants and Toddlers [J].

Amirav, Israel ;

Borojeni, Azadeh A. T. ;

Halamish, Asaf ;

Newhouse, Michael T. ;

Golshahi, Laleh .

PEDIATRIC PULMONOLOGY, 2015, 50 (03) :276-283

[3]

Ari A, 2010, RESP CARE, V55, P845

[4] Aerosol delivery through nasal cannulas:: An in vitro study [J].

Bhashyam, Abhiram R. ;

Wolf, Matthew T. ;

Marcinkowski, Amy L. ;

Saville, Al ;

Thomas, Kristina ;

Carcillo, Joseph A. ;

Corcoran, Timothy E. .

JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY, 2008, 21 (02) :181-187

[5] FACTORS INFLUENCING THE SIZE DISTRIBUTION OF AEROSOLS FROM JET NEBULIZERS [J].

CLAY, MM ;

PAVIA, D ;

NEWMAN, SP ;

CLARKE, SW .

THORAX, 1983, 38 (10) :755-759

[6]

Coates AL, 1998, PEDIATR PULM, V26, P412, DOI 10.1002/(SICI)1099-0496(199812)26:6<412::AID-PPUL6>3.0.CO

[7]

2-O

[8]

Cole C H, 2000, Respir Care, V45, P646

[9] Lung Deposition of 99mTc-Radiolabeled Albuterol Delivered through a Pressurized Metered Dose Inhaler and Spacer with Facemask or Mouthpiece in Children with Asthma [J].

Ditcham, William ;

Murdzoska, Jasminka ;

Zhang, Guicheng ;

Roller, Christina ;

von Hollen, Dirk ;

Nikander, Kurt ;

Devadason, Sunalene G. .

JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY, 2014, 27 :S63-S75

[10] Use of high flow nasal cannula in critically ill infants, children, and adults: a critical review of the literature [J].

Lee, Jan Hau ;

Rehder, Kyle J. ;

Williford, Lee ;

Cheifetz, Ira M. ;

Turner, David A. .

INTENSIVE CARE MEDICINE, 2013, 39 (02) :247-257

← 1 2 →