Physical Cues of Biomaterials Guide Stem Cell Differentiation Fate

被引：400

作者：

Higuchi, Akon ^{[1
,2
,3
]}

Ling, Qing-Dong ^{[3
,4
]}

Chang, Yung ^{[5
]}

Hsu, Shih-Tien ^{[6
]}

Umezawa, Akihiro ^{[2
]}

机构：

[1] Natl Cent Univ, Dept Chem & Mat Engn, Tao Yuan 32001, Taiwan

[2] Natl Res Inst Child Hlth & Dev, Dept Reprod Biol, Setagaya Ku, Tokyo 1578535, Japan

[3] Cathay Gen Hosp, Cathay Med Res Inst, Taipei 221, Taiwan

[4] Natl Cent Univ, Inst Syst Biol & Bioinformat, Tao Yuan 32001, Taiwan

[5] Chung Yuan Christian Univ, R&D Ctr Membrane Technol, Dept Chem Engn, Tao Yuan 320, Taiwan

[6] Taiwan Landseed Hosp, Pingjen City 32405, Tao Yuan County, Taiwan

来源：

CHEMICAL REVIEWS | 2013年 / 113卷 / 05期

关键词：

BASEMENT-MEMBRANE MATRIX; NEURAL PROGENITOR CELLS; OSTEOGENIC DIFFERENTIATION; EXTRACELLULAR-MATRIX; SMOOTH-MUSCLE; SELF-RENEWAL; NEURONAL DIFFERENTIATION; CHONDROGENIC DIFFERENTIATION; SELECTIVE DIFFERENTIATION; ELECTROSPUN NANOFIBERS;

D O I：

10.1021/cr300426x

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Millions of people lose or damage their organs or tissues due to disease, birth defects, or accidents each year. Stem cells, such as embryonic stem cells (ESC), induced pluripotent stem cells (iPSC), adult stem cells, and fetal stem cells are an attractive prospect for regenerative medicine and tissue engineering. The pluripotent nature of ESCs and iPSCs opens many avenues for potential stem cell-based regenerative therapies and the development of drug discovery platforms. Nowadays, it is difficult to find novel biomolecules for differentiation of stem cells and to find much higher efficiency of stem cell differentiation into desired lineages solely by combination of these biomolecules in culture medium. Biomaterials for stem cell culture are focused as a tool for finetuning of stem cell differentiation, because it is quite recent for researchers to realize biomaterials can guide stem cell fate of differentiation.

引用

页码：3297 / 3328

页数：32

共 229 条

[1] Nanoscale topography of the basement membrane underlying the corneal epithelium of the rhesus macaque [J].

Abrams, GA ;

Goodman, SL ;

Nealey, PF ;

Franco, M ;

Murphy, CJ .

CELL AND TISSUE RESEARCH, 2000, 299 (01) :39-46

[2] Functional immobilization of signaling proteins enables control of stem cell fate [J].

Alberti, Kristin ;

Davey, Ryan E. ;

Onishi, Kento ;

George, Sophia ;

Salchert, Katrin ;

Seib, F. Philipp ;

Bornhaeuser, Martin ;

Pompe, Tilo ;

Nagy, Andras ;

Werner, Carsten ;

Zandstra, Peter W. .

NATURE METHODS, 2008, 5 (07) :645-650

[3] Osteogenic Differentiation of Human Mesenchymal Stem Cells Directed by Extracellular Matrix-Mimicking Ligands in a Biomimetic Self-Assembled Peptide Amphiphile Nanomatrix [J].

Anderson, Joel M. ;

Kushwaha, Meenakshi ;

Tambralli, Ajay ;

Bellis, Susan L. ;

Camata, Renato P. ;

Jun, Ho-Wook .

BIOMACROMOLECULES, 2009, 10 (10) :2935-2944

[4]

Baker BM, 2011, TISSUE ENG PT A, V17, P1445, DOI [10.1089/ten.tea.2010.0535, 10.1089/ten.TEA.2010.0535]

[5] Direct and cell signaling-based, geometry-induced neuronal differentiation of neural stem cells [J].

Bakhru, Sasha ;

Nain, Amrinder S. ;

Highley, Christopher ;

Wang, Ji ;

Campbell, Phil ;

Amon, Cristina ;

Zappe, Stefan .

INTEGRATIVE BIOLOGY, 2011, 3 (12) :1207-1214

[6] Injectable Multidomain Peptide Nanofiber Hydrogel as a Delivery Agent for Stem Cell Secretome [J].

Bakota, Erica L. ;

Wang, Yin ;

Danesh, Farhad R. ;

Hartgerink, Jeffrey D. .

BIOMACROMOLECULES, 2011, 12 (05) :1651-1657

[7] Biopolymer-Based Hydrogels for Cartilage Tissue Engineering [J].

Balakrishnan, Biji ;

Banerjee, R. .

CHEMICAL REVIEWS, 2011, 111 (08) :4453-4474

[8] The influence of hydrogel modulus on the proliferation and differentiation of encapsulated neural stem cells [J].

Banerjee, Akhilesh ;

Arha, Manish ;

Choudhary, Soumitra ;

Ashton, Randolph S. ;

Bhatia, Surita R. ;

Schaffer, David V. ;

Kane, Ravi S. .

BIOMATERIALS, 2009, 30 (27) :4695-4699

[9] Control of human embryonic stem cell colony and aggregate size heterogeneity influences differentiation trajectories [J].

Bauwens, Celine Liu ;

Peerani, Raheem ;

Niebruegge, Sylvia ;

Woodhouse, Kimberly A. ;

Kumacheva, Eugenia ;

Husain, Mansoor ;

Zandstra, Peter W. .

STEM CELLS, 2008, 26 (09) :2300-2310

[10] Engineering of adult human neural stem cells differentiation through surface micropatterning [J].

Beduer, Amelie ;

Vieu, Christophe ;

Arnauduc, Florent ;

Sol, Jean-Christophe ;

Loubinoux, Isabelle ;

Vaysse, Laurence .

BIOMATERIALS, 2012, 33 (02) :504-514

← 1 2 3 4 5 6 7 8 9 10 →