The Nitro to Carbonyl Conversion (Nef Reaction): New Perspectives for a Classical Transformation

被引：137

作者：

Ballini, Roberto ^{[1
]}

Petrini, Marino ^{[1
]}

机构：

[1] Univ Camerino, Sch Sci & Technol, Div Chem, I-62032 Camerino, Italy

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2015年 / 357卷 / 11期

关键词：

carbonyl derivatives; nitroalkanes; nitroalkenes; oxidation; reduction; ONE-POT SYNTHESIS; ASYMMETRIC CONJUGATE ADDITION; RING-OPENING REACTIONS; AZA-HENRY REACTIONS; ALPHA-AMINO-ACIDS; ENANTIOSELECTIVE SYNTHESIS; EFFICIENT SYNTHESIS; SECONDARY NITROALKANES; MICHAEL ADDITION; GAMMA-LACTONES;

D O I：

10.1002/adsc.201500008

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

This review article reports new procedures and practical application of the nitro to carbonyl conversion that appeared in the literature after our comprehensive report published in 2004. Beside traditional and well explored reactant systems, new procedures including the utilization of molecular oxygen and photoredox catalysis have been introduced for the Nef reaction. Of notable interest is the utilization of the nitro to carbonyl conversion in tandem and cascade processes aimed at the preparation of hetero and carbocyclic derivatives.

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页码：2371 / 2402

页数：32

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