Epidemiologic Investigations into Outbreaks of Rift Valley Fever in Humans, South Africa, 2008-2011

被引:58
作者
Archer, Brett N. [1 ]
Thomas, Juno [1 ,2 ]
Weyer, Jacqueline [1 ]
Cengimbo, Ayanda [1 ]
Landoh, Dadja E. [3 ,4 ]
Jacobs, Charlene [1 ]
Ntuli, Sindile [1 ]
Modise, Motshabi [3 ]
Mathonsi, Moshe [3 ]
Mashishi, Morton S. [3 ]
Leman, Patricia A. [1 ]
le Roux, Chantel [1 ]
van Vuren, Petrus Jansen [1 ]
Kemp, Alan [1 ]
Paweska, Janusz T. [1 ]
Blumberg, Lucille [1 ,2 ]
机构
[1] NICD, NHLS, ZA-2131 Johannesburg, Gauteng, South Africa
[2] Univ Witwatersrand, Johannesburg, South Africa
[3] Univ Pretoria, NICD, NHLS, Sch Hlth Syst & Publ Hlth, ZA-0002 Pretoria, South Africa
[4] Minist Sante, Lome, Togo
关键词
NORTHEASTERN KENYA; VIRUS; ANTIBODY;
D O I
10.3201/eid1912.121527
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Rift Valley fever (RVF) is an emerging zoonosis posing a public health threat to humans in Africa. During sporadic RVF outbreaks in 2008-2009 and widespread epidemics in 2010-2011,302 laboratory-confirmed human infections, including 25 deaths (case-fatality rate, 8%) were identified. Incidence peaked in late summer to early autumn each year, which coincided with incidence rate patterns in livestock. Most case-patients were adults (median age 43 year's), men (262; 87%), who worked in farming, animal health or meat-related industries (83%). Most case-patients reported direct contact with animal tissues, blood, or other body fluids before onset of illness (89%); mosquitoes likely played a limited role in transmissibn of disease to humans. Close. partnership with animal health and agriculture sectors allowed early recognition of human cases and appropriate preventive health messaging.
引用
收藏
页码:1918 / 1925
页数:8
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