Synthesis, Spectroscopic and Antimicrobial Assessments of Cu(II), Co(II), Ni(II) and Pb(II) Clioquinol Complexes

被引：1

作者：

Fetooh, Hammad ^{[1
]}

机构：

[1] Zagazig Univ, Fac Sci, Dept Chem, Zagazig, Egypt

来源：

EGYPTIAN JOURNAL OF CHEMISTRY | 2020年 / 63卷 / 05期

关键词：

Clioquinol; FTIR; Thermal analyses; Electronic spectra; Antimicrobial activity; ALZHEIMERS-DISEASE; IDENTIFICATION; TOXICITY; SPECTRA;

D O I：

10.21608/ejchem.2019.17709.2087

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

OUR goal in this article is to synthesize of four novel clioquinol (Clio) drug complexes for the Co(II), Ni(II), Cu(II) in addition to Pb(II) . On the basis of spectroscopic, magnetic, conductance and thermal studies, the complexes have been characterized. Free ligand acts as abidentate chelate with metal ions through its two atoms Oxygen in addition to nitrogen. Structural formulas for Clio complexes have chemical formulas [Co(Clio)(2)(H2O)(2)]center dot 2H(2)O, [Ni(Clio)(2)(H2O)(2)]center dot H2O, [Cu(Clio)(2)(H2O)(2)]center dot H2O in addition to [Pb(Clio)(2)]center dot 2H(2)O. The thermal decomposition of all complexes contains metal oxides as a residue in its final degradation steps. The antimicrobial activities of the complexes are in a good assessment and the synthesized complexes have a higher activity with lipophilic nature against bacteria and fungi.

引用

页码：1811 / 1822

页数：12

共 29 条

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