The Obesity Epidemic and Its Impact on Hypertension

被引:152
作者
Nguyen, Thang [4 ]
Lau, David C. W. [1 ,2 ,3 ]
机构
[1] Univ Calgary, Julia McFarlane Diabet Res Ctr, Dept Med, Calgary, AB T2N 4N1, Canada
[2] Univ Calgary, Julia McFarlane Diabet Res Ctr, Dept Biochem & Mol Biol, Calgary, AB T2N 4N1, Canada
[3] Univ Calgary, Julia McFarlane Diabet Res Ctr, Dept Cardiac Sci, Calgary, AB T2N 4N1, Canada
[4] St Michaels Hosp, Div Cardiol Cardiac Prevent & Rehabil, Toronto, ON M5B 1W8, Canada
基金
加拿大健康研究院;
关键词
BODY-MASS INDEX; CARDIOVASCULAR RISK-FACTORS; Y GASTRIC BYPASS; LAPAROSCOPIC SLEEVE GASTRECTOMY; QUALITY-OF-LIFE; BLOOD-PRESSURE; WEIGHT-LOSS; CARDIOMETABOLIC RISK; METABOLIC SYNDROME; OVERWEIGHT;
D O I
10.1016/j.cjca.2012.01.001
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Global obesity rates have increased steadily in both developed and emerging countries over the past several decades with little signs of slowing down. Over 1.5 billion people worldwide are overweight or obese and over 40 million children under the age of 5 are overweight. Obesity is associated with increased morbidity, disability, and premature mortality from cardiovascular disease, diabetes, cancers, and musculoskeletal disorders. The personal and societal health and economic burden of this preventable disease pose a serious threat to our societies. Obesity is a major risk factor for hypertension and cardiovascular disease. Weight loss, through health behaviour modification and dietary sodium restriction, is the cornerstone in the treatment of obesity-related hypertension. Pharmacotherapy and bariatric surgery for obesity are adjunctive measures when health behaviour interventions fail to achieve the body weight and health targets. Successful management of overweight and obese persons requires a comprehensive, multifaceted framework that integrates population health, public health, and medical health models to dismantle the proximal and distal drivers of the obesogenic environment in which we live. Prevention of obesity is no longer a lofty but rather necessary goal that urgently calls for action from governments at all levels, in conjunction with all public and private sector stakeholders, in order to combat a serious and growing public health concern.
引用
收藏
页码:326 / 333
页数:8
相关论文
共 68 条
  • [1] Obesity and overweight in Canada: an updated cost-of-illness study
    Anis, A. H.
    Zhang, W.
    Bansback, N.
    Guh, D. P.
    Amarsi, Z.
    Birmingham, C. L.
    [J]. OBESITY REVIEWS, 2010, 11 (01) : 31 - 40
  • [2] [Anonymous], 2008, Global Health Risks Mortality and burden of disease attributable to selected major risks
  • [3] [Anonymous], 2011, OB CAN
  • [4] Dietary approaches to prevent and treat hypertension - A scientific statement from the American Heart Association
    Appel, LJ
    Brands, MW
    Daniels, SR
    Karanja, N
    Elmer, PJ
    Sacks, FM
    [J]. HYPERTENSION, 2006, 47 (02) : 296 - 308
  • [5] Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study
    Astrup, Arne
    Rossner, Stephan
    Van Gaal, Luc
    Rissanen, Aila
    Niskanen, Leo
    Al Hakim, Mazin
    Madsen, Jesper
    Rasmussen, Mads F.
    Lean, Michael E. J.
    [J]. LANCET, 2009, 374 (9701) : 1606 - 1616
  • [6] Childhood body-mass index and the risk of coronary heart disease in adulthood
    Baker, Jennifer L.
    Olsen, Lina W.
    Sorensen, Thorkild I. A.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (23) : 2329 - 2337
  • [7] Early results of a Canadian laparoscopic sleeve gastrectomy experience
    Behrens, Carola
    Tang, Bao Q.
    Amson, Bradley J.
    [J]. CANADIAN JOURNAL OF SURGERY, 2011, 54 (02) : 138 - 143
  • [8] Oxidative stress, nitric oxide production, and renal sodium handling in leptin-induced hypertension
    Beltowski, J
    Wójcicka, G
    Marciniak, A
    Jamroz, A
    [J]. LIFE SCIENCES, 2004, 74 (24) : 2987 - 3000
  • [9] Laparoscopic sleeve gastrectomy and laparoscopic gastric bypass are equally effective for reduction of cardiovascular risk in severely obese patients at one year of follow-up
    Benaiges, David
    Goday, Albert
    Ramon, Jose M.
    Hernandez, Elisa
    Pera, Manuel
    Cano, Juan F.
    [J]. SURGERY FOR OBESITY AND RELATED DISEASES, 2011, 7 (05) : 575 - 580
  • [10] Adolescent overweight and future adult coronary heart disease
    Bibbins-Domingo, Kirsten
    Coxson, Pamela
    Pletcher, Mark J.
    Lightwood, James
    Goldman, Lee
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (23) : 2371 - 2379