USE OF NaOH AS A NEW ACTIVATOR FOR THE PALLADIUM-CATALYZED DIRECT CH ARYLATION OF THIAZOLE DERIVATIVES

被引：19

作者：

Miyaoku, Takayuki ^{[1
]}

Mori, Atsunori ^{[1
]}

机构：

[1] Kobe Univ, Dept Chem Sci & Engn, Nada Ku, Kobe, Hyogo 6578501, Japan

来源：

HETEROCYCLES | 2009年 / 77卷 / 01期

关键词：

Thiazole; CH Arylation; Sodium Hydroxide; Bulky Phosphine; Aryl Bromide; ARYL HALIDES; 2,5-DIARYLTHIAZOLE; BROMOTHIOPHENE; AZOLES;

D O I：

10.3987/COM-08-S(F)5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Sodium hydroxide is found to serve as a new activator for the palladium-catalyzed C-H arylation of thiazole derivatives with aryl bromides and aryl iodides. The reaction of benzothiazole proceeds smoothly with 4-bromoanisole to afford the corresponding coupling product in an excellent yield.

引用

页码：151 / 155

页数：5

共 32 条

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