Seroprevalence of Antibodies to Measles, Mumps, and Rubella among Thai Population: Evaluation of Measles/MMR Immunization Programme

被引：28

作者：

Tharmaphornpilas, Piyanit ^{[1
]}

Yoocharean, Pornsak ^{[1
]}

Rasdjarmrearnsook, Aim-orn ^{[1
]}

Theamboonlers, Apiradee ^{[2
]}

Poovorawan, Yong ^{[2
]}

机构：

[1] Minist Publ Hlth, Dept Dis Control, Bur Gen Communicable Dis, Nonthaburi 11000, Thailand

[2] Chulalongkorn Univ, Fac Med, Dept Paediat, Ctr Excellence Clin Virol, Bangkok 10330, Thailand

来源：

JOURNAL OF HEALTH POPULATION AND NUTRITION | 2009年 / 27卷 / 01期

关键词：

Antibodies; Immunization; Measles; Measles vaccine; Mumps; MMR vaccine; Rubella; Seroepidemiologic studies; Seroprevalence; Vaccination; Thailand; VACCINE; IMMUNITY; SEROEPIDEMIOLOGY; VIRUS; AGE;

D O I：

10.3329/jhpn.v27i1.3320

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Stored serum specimens, from four regions of Thailand, of healthy children attending well baby clinics and of healthy people with acute illnesses visiting outpatient clinics were randomly sampled and tested for IgG antibody to measles, mumps, and rubella (MMR). The immunity patterns of rubella and mumps fitted well with the history of rubella and MMR vaccination, seroprotective rates being over 85% among those aged over seven years. A high proportion of younger children acquired the infection before the age of vaccination. MMR vaccination should preferably be given to children at an earlier age. For measles, 73% seroprotective rates among children, aged 8-14 years, who should have received two doses of measles/MMR vaccine, were lower than expected. This finding was consistent with the age-group reported in outbreaks of measles in Thailand. The apparent ineffectiveness (in relation to measles) of MMR immunization of 1(st) grade students warrants further studies.

引用

页码：80 / 86

页数：7