Changing epidemiology of non-albicans candidemia in Korea

被引:25
作者
Ko, Jae-Hoon [1 ,9 ]
Jung, Dong Sik [2 ]
Lee, Ji Yeon [3 ]
Kim, Hyun Ah [3 ]
Ryu, Seong Yeol [3 ]
Jung, Sook-In [4 ]
Joo, Eun-Jeong [5 ]
Cheon, Shinhye [6 ]
Kim, Yeon-Sook [6 ]
Kim, Shin-Woo [7 ]
Cho, Sun Young [1 ]
Kang, Cheol-In [1 ]
Chung, Doo Ryeon [1 ]
Lee, Nam Yong [8 ]
Peck, Kyong Ran [1 ]
机构
[1] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Div Infect Dis,Dept Med, 81 Irwon Ro, Seoul 06531, South Korea
[2] Dong A Univ, Coll Med, Div Infect Dis, Busan, South Korea
[3] Keimyung Univ, Dongsan Med Ctr, Div Infect Dis, Daegu, South Korea
[4] Chonnam Natl Univ Hosp, Div Infect Dis, Gwangju, South Korea
[5] Sungkyunkwan Univ, Kangbuk Samsung Hosp, Sch Med, Div Infect Dis,Dept Internal Med, Seoul, South Korea
[6] Chungnam Natl Univ, Sch Med, Div Infect Dis, Daejeon, South Korea
[7] Kyungpook Natl Univ, Sch Med, Div Infect Dis, Daegu, South Korea
[8] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Lab Med, Seoul, South Korea
[9] Armed Forces Capital Hosp, Dept Internal Med, Div Infect Dis, Seongnam, South Korea
关键词
Epidemiology; non-albicans Candida; Antifungal resistance; Candida glabrata; Candida parapsilosis; ANTIFUNGAL SUSCEPTIBILITY; SPECIES DISTRIBUTION; AMPHOTERICIN-B; HOSPITALS; VORICONAZOLE; FLUCONAZOLE; GLABRATA;
D O I
10.1016/j.jiac.2018.09.016
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
An epidemiologic surveillance of non-albicans candidemia for a 6-year period was conducted in Korea. Compared to the published epidemiologic data for the previous 6 years, an increase of C. glabrata (from 21.3% to 28.5%) and a decrease of C. parapsilosis (from 36.5% to 24.7%) were noticed. During the study period, C. tropicalis (36.4%) was most frequently isolated non-albicans Candida, followed by C. glabrata (28.5%), C. parapsilosis (24.7%), and C. krusei (2.6%). Replacement of primary amphotericin B treatment with echinocandins (P < 0.001) eliminated amphotericin B resistance (from 7.8% in 2011 to 0% in 2014). (c) 2018 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:388 / 391
页数:4
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