Identification of DTYMK and CHEK1 as therapeutic targets in LKB1 mutant non-small cell lung cancer

被引：0
|
作者：
Liu, Yan [1 ]
Cowley, Glenn S. [2 ]
Cohoon, Travis J. [1 ]
Root, David E. [2 ]
Kwok-kin, Wong [1 ]
机构：
[1] Dana Farber Canc Inst, Boston, MA 02115 USA
[2] Broad Inst, Boston, MA USA
来源：
CANCER RESEARCH | 2012年 / 72卷
关键词：
D O I：
10.1158/1538-7445.AM2012-LB-260
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
LB-260
引用
收藏
页数：1
相关论文
共 50 条
  • [11] Unraveling the Role of STK11/LKB1 in Non-small Cell Lung Cancer
    Sumbly, Vikram
    Landry, Ian
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2022, 14 (01)
  • [12] Tumor Angiogenesis in LKB1-Mutant Non-Small Cell Lung Cancer (NSCLC)
    Guijarro, Irene
    Nilsson, Monique
    Poteete, Alissa
    Tong, Pan
    Sun, Huiying
    Denning, Warren
    Xia, Dianren
    Skoulidis, Ferdinandos
    Wang, Jing
    Roarty, Emily
    Heymach, John V.
    JOURNAL OF THORACIC ONCOLOGY, 2015, 10 (09) : S296 - S296
  • [13] LKB1 loss sensitizes non-small cell lung cancer cells to aggravation of ER stress
    Inge, Landon J.
    Friel, Jacqueline M.
    Fowler, Aaron
    Richer, Amanda
    Whitsett, Timothy
    Tran, Nhan L.
    Bremner, Ross M.
    CANCER RESEARCH, 2014, 74 (19)
  • [14] LKB1 inactivation sensitizes non-small cell lung cancer to pharmacological aggravation of ER stress
    Inge, Landon J.
    Friel, Jacqueline M.
    Richer, Amanda L.
    Fowler, Aaron J.
    Whitsett, Timothy
    Smith, Michael A.
    Tran, Nhan L.
    Bremner, Ross M.
    CANCER LETTERS, 2014, 352 (02) : 187 - 195
  • [15] STK11/LKB1 mutation in non-small cell lung cancer: Prognostic or predictive?
    Rosellini, P.
    Girodet, P. O.
    FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2023, 37 : 50 - 51
  • [16] LKB1 loss is associated with resistance to VEGF inhibitors in non-small cell lung cancer (NSCLC)
    Guijarro, Irene
    Poteete, Alissa
    Yang, Chao
    Roarty, Emily
    Nilsson, Monique
    Sun, Huiying
    Tong, Pan
    Chang, Edward
    Rodriguez-Canales, Jaime
    Mino, Barbara
    Parra, Edwin
    Wistuba, Ignacio
    Wang, Jing
    Heffernan, Timothy
    Heymach, John V.
    CANCER RESEARCH, 2016, 76
  • [17] Identification of New Therapeutic Targets in Non-Small Cell Lung Cancer
    O'Donnell, K. A.
    JOURNAL OF THORACIC ONCOLOGY, 2020, 15 (02) : S4 - S4
  • [18] LKB1 mutations are extremely rare in Korean non-small cell lung cancers
    Kim, Min Jung
    Jin, Guang
    Jheon, Hyo-Sung
    Lee, Sin Yup
    Cha, Sung Ick
    Kim, Chang Ho
    Jung, Tae Noon
    Park, Jae Yong
    CANCER GENETICS AND CYTOGENETICS, 2010, 196 (02) : 204 - 206
  • [19] Phenformin combines with selumetinib in targeting KRAS mutant non-small cell lung cancer cells with alternative LKB1 status.
    Zhang, Jun
    Wang, Dongsheng
    Qian, Guoqing
    Liu, Fakeng
    Rahman, Mohammad Aminur
    Nannapaneni, Sreevinas
    Wang, Xu
    Peng, Xianghong
    Chen, Zhuo Georgia
    Wong, Kwok-Kin
    Khuri, Fadlo Raja
    Zhou, Wei
    Shin, Dong Moon
    JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)
  • [20] Metabolic barriers in non-small cell lung cancer with LKB1 and/or KEAP1 mutations for immunotherapeutic strategies
    Tanaka, Ichidai
    Koyama, Junji
    Itoigawa, Hideyuki
    Hayai, Shunsaku
    Morise, Masahiro
    FRONTIERS IN ONCOLOGY, 2023, 13
12345