Catalyst-Free [3+2] Cycloaddition of Electron-Deficient Alkynes and o-Hydroxyaryl Azomethine Ylides in Water

被引：8

作者：

Zhu, Jin ^{[1
]}

Su, Wenbo ^{[1
]}

Xiong, Cheng ^{[1
]}

Bai, Ruifang ^{[1
]}

Zhou, Qingfa ^{[1
]}

Chen, Ming ^{[1
]}

机构：

[1] China Pharmaceut Univ, Dept Organ Chem, State Key Lab Nat Med, Nanjing 210009, Peoples R China

来源：

ACS OMEGA | 2020年 / 5卷 / 29期

基金：

中国国家自然科学基金;

关键词：

1,3-DIPOLAR CYCLOADDITION; ASYMMETRIC-SYNTHESIS; CONSTRUCTION; HETEROCYCLES; DERIVATIVES; PAX3-FOXO1; ESTERS;

D O I：

10.1021/acsomega.0c01856

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A catalyst-free [3 + 2] cycloaddition reaction of electron-deficient alkynes and o-hydroxyaryl azomethine ylides in water was developed, affording pyrroline derivatives in moderate to high yields (up to 90%).

引用

页码：18244 / 18253

页数：10

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