Association Between Serum Free Fatty Acids Levels and Gestational Diabetes Mellitus: a Cross-Sectional Study

被引：3

作者：

Zhang, Juanwen ^{[1
]}

Yao, Jinmei ^{[1
]}

Zhao, Ying ^{[1
]}

Zheng, Nengneng ^{[2
]}

Dai, Yuying ^{[3
]}

机构：

[1] Zhejiang Univ, Affiliated Hosp 1, Dept Lab Med, Coll Med, Hangzhou 310003, Zhejiang, Peoples R China

[2] Tongde Hosp Zhejiang Prov, Dept Gynecol & Obstet, Hangzhou 310012, Zhejiang, Peoples R China

[3] Zhejiang Med Coll, Dept Clin Med, 481 Binwen Rd, Hangzhou 310053, Zhejiang, Peoples R China

来源：

CLINICAL LABORATORY | 2017年 / 63卷 / 01期

关键词：

gestational diabetes mellitus; insulin resistance; free fatty acids; METABOLIC SYNDROME; PREGNANCY; LIPOLYSIS; STRESS; RISK;

D O I：

10.7754/Clin.Lab.2016.160312

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Background: This study aimed to assess the relationship between serum free fatty acid (FFA) levels and gestational diabetes mellitus (GDM) in Chinese pregnant women. Methods: A cross-sectional study was performed among 779 eligible pregnant women who underwent detailed prenatal visits in Hangzhou, China. Results: Patients with GDM had significantly higher serum FFA levels than those without GDM. Spearman's correlation analysis showed that FFA levels were positively correlated with fasting plasma glucose, 1hPG, 2hPG, HOMA-IR, triglyceride, and sialic acid (p < 0.05) and negatively correlated with serum amylase level (all with p < 0.05). Stepwise logistic regression analysis further showed that elevated FFA levels significantly contributed to the risk for GDM. Conclusions: Our findings suggested that serum FFA levels were significantly associated with GDM.

引用

页码：15 / 20

页数：6

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