Nitrilium ions - synthesis and applications

被引：49

作者：

van Dijk, Tom ^{[1
]}

Slootweg, J. Chris ^{[1
,3
]}

Lammertsma, Koop ^{[1
,2
]}

机构：

[1] Vrije Univ Amsterdam, Dept Chem & Pharmaceut Sci, De Boelelaan 1083, NL-1081 HV Amsterdam, Netherlands

[2] Univ Johannesburg, Dept Chem, Auckland Pk, ZA-2006 Johannesburg, South Africa

[3] Univ Amsterdam, Vant Hoff Inst Mol Sci, Sci Pk 904,POB 94157, NL-1090 GD Amsterdam, Netherlands

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2017年 / 15卷 / 48期

关键词：

N-ARYLNITRILIUM SALTS; ISOCYANIDE-BASED MCR; TRIFLUOROMETHANESULFONATE SALTS; X-RAY; PHOTOCHEMICAL GENERATION; MULTICOMPONENT REACTIONS; CATALYZED DECOMPOSITION; DIAZOCARBONYL COMPOUNDS; BECKMANN REARRANGEMENT; 3-COMPONENT SYNTHESIS;

D O I：

10.1039/c7ob02533e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Nitrilium ions have been well-established in organic chemistry for many decades, but recent developments show them to be far more versatile than hitherto recognized. They are known as stable salts, can be generated in situ, or are present as transient intermediates. We provide a succinct, but comprehensive review on the synthesis, stability, and reactivity of nitrilium ions as synthons for imines, their use in the synthesis of a large spectrum of heterocycles, and their reactions with transition metal complexes. By offering this overview, we aim for a renewed focus on readily accessible and simple to use nitrilium ions as valuable reagents for the synthesis of organic compounds.

引用

页码：10134 / 10144

页数：11

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