Prazosin for Military Combat-Related PTSD Nightmares: A Critical Review

被引:25
作者
Writer, Brian W. [1 ]
Meyer, Eric G. [1 ]
Schillerstrom, Jason E. [1 ]
机构
[1] Joint Base San Antonio, Wilford Hall Ambulatory Surg Ctr, Dept Psychiat, San Antonio, TX 78236 USA
关键词
POSTTRAUMATIC-STRESS-DISORDER; NATIONAL EPIDEMIOLOGIC SURVEY; SLEEP DISTURBANCE; TRAUMA NIGHTMARES; WAVE; VETERANS; SYMPTOMS; ADULTS; DEPLOYMENT; SOLDIERS;
D O I
10.1176/appi.neuropsych.13010006
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Military combat is a common trauma experience associated with posttraumatic stress disorder (PTSD). Trauma-related nightmares are a hallmark symptom of PTSD. They can be resistant to label-pharmacological PTSD treatment, and they are associated with a variety of adverse health outcomes. The purpose of this article is to review and evaluate prazosin therapy for combat-related PTSD nightmares. Consistent with available literature for all-causes PTSD nightmares, prazosin is an effective off-label option for combat-related PTSD nightmares. Future trials may further instruct use in specific combat-exposure profiles.
引用
收藏
页码:24 / 33
页数:10
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