Role of Age and Sex in the Diagnosis of Early-stage Malignant Melanoma: A Cross-sectional Study

被引：5
|
作者：
Moreno-Ramirez, David [1 ]
Ojeda-Vila, Teresa [1 ]
Rios-Martin, Juan J. [2 ]
Nieto-Garcia, Adoracion [3 ]
Ferrandiz, Lara [1 ]
机构：
[1] Hosp Univ Virgen Macarena, Dermatol Unit, ES-41009 Seville, Spain
[2] Hosp Univ Virgen Macarena, Pathol Unit, ES-41009 Seville, Spain
[3] Univ Seville, Sch Med, Publ Hlth & Epidemiol Dept, Seville, Spain
来源：
ACTA DERMATO-VENEREOLOGICA | 2015年 / 95卷 / 08期
关键词：
malignant melanoma; prognostic predictors; thin melanoma; early-stage malignant melanoma; age; sex; CUTANEOUS MELANOMA; DETERMINANTS; PROGNOSIS;
D O I：
10.2340/00015555-2115
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Age and sex have been identified as predictors of outcome in malignant melanoma (MM). The aim of this multicentre, cross-sectional study was to analyse the role of age and sex as explanatory variables for the diagnosis of thin MM. A total of 2,430 patients with MM were recruited. Cases of in situ (Tis) and T1 MM were more frequent than T2-T4 MM (56.26% vs. 43.74%). Breslow thickness increased throughout decades of life (analysis of variance (ANOVA) p<0.001), with a weak correlation between Breslow thickness and patient's age (r=0.202, p<0.001). Breslow thickness was significantly less in women (1.79 vs. 2.38 mm, p=0.0001). Binary logistic regression showed a significant (p<0.001) odds ratio for age 0-29 years (1.18), and 30-59 years (1.16), and for women (1.09). Age and sex explained 3.64% of the variation observed in Tis-T1 frequency (R-2=0.0364). Age and sex appear to explain a low percentage of the variation in the early detection of MM.
引用
收藏
页码：940 / 942
页数：3
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