Antioxidant activity with flavonoidal constituents from Aerva persica

被引：24

作者：

Ahmed, Ejaz

Imran, Muhammad

Malik, Abdul ^{[1
]}

Ashraf, Muhammad

机构：

[1] Univ Karachi, HEJ Res Inst Chem, Int Ctr Chem Sci, Karachi 75270, Pakistan

[2] Islamia Univ Bahawalpur, Dept Pharm, Islamabad, Pakistan

来源：

ARCHIVES OF PHARMACAL RESEARCH | 2006年 / 29卷 / 05期

关键词：

Aerva persica; amaranthaceae; persinol; persinoside A; persinoside B; antioxidant activities;

D O I：

10.1007/BF02968582

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A new flavanone Persinol (1) and the new flavanone glucosides persinosides A (2) and B (3), along with known flavonoids (4 and 5) have been isolated from the ethyl acetate soluble fraction of the whole plants of Aerva persica. Their structures were elucidated on the basis of extensive analysis of nuclear magnetic resonance (1 D & 2D-NMR) spectral data. All of them showed profound antioxidative activities by DPPH and cytochrome-c-reduction assays using the HL-60 cell culture system.

引用

收藏

页码：343 / 347

页数：5

相关论文

共 20 条

[1] Structure-activity relationships for antioxidant activities of a series of flavonoids in a liposomal system [J].

Arora, A ;

Nair, MG ;

Strasburg, GM .

FREE RADICAL BIOLOGY AND MEDICINE, 1998, 24 (09) :1355-1363

[2] Antioxidant and prooxidant behavior of flavonoids: Structure-activity relationships [J].

Cao, GH ;

Sofic, E ;

Prior, RL .

FREE RADICAL BIOLOGY AND MEDICINE, 1997, 22 (05) :749-760

[3]

FORKMANN G, 1983, Z NATURFORSCH C, V38, P891

[4] CIRCULAR DICHROISM, OPTICAL ROTATORY DISPERSION AND ABSOLUTE CONFIGURATION OF FLAVANONES, 3-HYDROXYFLAVANONES AND THEIR GLYCOSIDES - DETERMINATION OF AGLYCONE CHIRALITY IN FLAVANONE GLYCOSIDES [J].

GAFFIELD, W .

TETRAHEDRON, 1970, 26 (17) :4093-&

[5]

GARG SP, 1979, INDIAN J CHEM B, V17, P416

[6] AERVANONE, A NEW FLAVANONE FROM AERVA-PERSICA [J].

GARG, SP ;

BHUSHAN, R ;

KAPOOR, RC .

PHYTOCHEMISTRY, 1980, 19 (06) :1265-1267

[7] CONSTITUENTS OF THE COMPOSITAE .45. PHENOLIC DERIVATIVES FROM ARTEMISIA-GLUTINOSA [J].

GONZALEZ, AG ;

BERMEJO, J ;

ESTEVEZ, F ;

VELAZQUEZ, R .

PHYTOCHEMISTRY, 1983, 22 (06) :1515-1516

[8] FURTHER STUDIES ON ASSIGNMENT OF SIGNALS IN C-13 MAGNETIC-RESONANCE SPECTRA OF ALDOSES AND DERIVED METHYL GLYCOSIDES [J].

GORIN, PAJ ;

MAZUREK, M .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1975, 53 (08) :1212-1223

[9] GLUCOSYLATED FLAVONOIDS AND OTHER PHENOLIC-COMPOUNDS FROM SORGHUM [J].

GUJER, R ;

MAGNOLATO, D ;

SELF, R .

PHYTOCHEMISTRY, 1986, 25 (06) :1431-1436

[10] FLAVONOIDS OF CITRUS .4. ISOLATION OF SOME AGLYCONES FROM THE LEMON (CITRUS-LIMON) [J].

HOROWITZ, RM ;

GENTILI, B .

JOURNAL OF ORGANIC CHEMISTRY, 1960, 25 (12) :2183-2187