Microwave assisted synthesis of amorphous magnesium phosphate nanospheres

被引：53

作者：

Zhou, Huan ^{[1
]}

Luchini, Timothy J. F. ^{[1
]}

Bhaduri, Sarit B. ^{[1
,2
]}

机构：

[1] Univ Toledo, Dept Mech Ind & Mfg Engn, Toledo, OH 43606 USA

[2] Univ Toledo, Dept Surg, Toledo, OH 43606 USA

来源：

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE | 2012年 / 23卷 / 12期

关键词：

CALCIUM-PHOSPHATE; BONE REGENERATION; IN-VITRO; TEMPERATURE; NANOPARTICLES; BIOMATERIALS; FABRICATION;

D O I：

10.1007/s10856-012-4743-y

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Magnesium phosphate (MgP) materials have been investigated in recent years for tissue engineering applications, attributed to their biocompatibility and biodegradability. This paper describes a novel microwave assisted approach to produce amorphous magnesium phosphate (AMP) in a nanospherical form from an aqueous solution containing Mg2+ and HPO4 (2-)/PO4 (3-). Some synthesis parameters such as pH, Mg/P ratio, solution composition were studied and the mechanism of AMP precursors was also demonstrated. The as-produced AMP nanospheres were characterized and tested in vitro. The results proved these AMP nanospheres can self-assemble into mature MgP materials and support cell proliferation. It is expected such AMP has potential in biomedical applications.

引用

页码：2831 / 2837

页数：7

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