Exosome Therapy for Stroke

被引：135
作者：
Chen, Jieli [1 ,2 ,3 ]
Chopp, Michael [1 ,4 ]
机构：
[1] Henry Ford Hosp, Dept Neurol, E&R Bldg,Room 3067,2799 W Grand Blvd, Detroit, MI 48202 USA
[2] Tianjin Med Univ Gen Hosp, Dept Geriatr, Tianjin, Peoples R China
[3] Minist Educ, Tianjin Neurol Inst, Key Lab Postneurotrauma Neurorepair & Regenerat C, Beijing, Peoples R China
[4] Oakland Univ, Dept Phys, Rochester, MI USA
来源：
STROKE | 2018年 / 49卷 / 05期
关键词：
exosomes; lipids; mesenchymal stromal cells; microRNAs; stroke; MESENCHYMAL STROMAL CELLS; HUMAN BONE-MARROW; EXTRACELLULAR VESICLES EXOSOMES; IMMUNOAFFINITY CAPTURE METHODS; DENSITY-GRADIENT SEPARATION; TRAUMATIC BRAIN-INJURY; STEM-CELL; CARDIOVASCULAR-DISEASE; FUNCTIONAL RECOVERY; MEDIATED ENDOCYTOSIS;
D O I：
10.1161/STROKEAHA.117.018292
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
[No abstract available]
引用
收藏
页码：1083 / 1090
页数：8
相关论文
共 106 条
[91]   MicroRNA cluster miR-17-92 Cluster in Exosomes Enhance Neuroplasticity and Functional Recovery After Stroke in Rats [J].
Xin, Hongqi ;
Katakowski, Mark ;
Wang, Fengjie ;
Qian, Jian-Yong ;
Liu, Xian Shuang ;
Ali, Meser M. ;
Buller, Benjamin ;
Zhang, Zheng Gang ;
Chopp, Michael .
STROKE, 2017, 48 (03) :747-753
[92]   Secondary Release of Exosomes From Astrocytes Contributes to the Increase in Neural Plasticity and Improvement of Functional Recovery After Stroke in Rats Treated With Exosomes Harvested From MicroRNA 133b-Overexpressing Multipotent Mesenchymal Stromal Cells [J].
Xin, Hongqi ;
Wang, Fengjie ;
Li, Yanfeng ;
Lu, Qing-e ;
Cheung, Wing Lee ;
Zhang, Yi ;
Zhang, Zheng Gang ;
Choppt, Michael .
CELL TRANSPLANTATION, 2017, 26 (02) :243-257
[93]   Exosomes/miRNAs as mediating cell-based therapy of stroke [J].
Xin, Hongqi ;
Li, Yi ;
Chopp, Michael .
FRONTIERS IN CELLULAR NEUROSCIENCE, 2014, 8
[94]   MiR-133b Promotes Neural Plasticity and Functional Recovery After Treatment of Stroke with Multipotent Mesenchymal Stromal Cells in Rats Via Transfer of Exosome-Enriched Extracellular Particles [J].
Xin, Hongqi ;
Li, Yi ;
Liu, Zhongwu ;
Wang, Xinli ;
Shang, Xia ;
Cui, Yisheng ;
Zhang, Zheng Gang ;
Chopp, Michael .
STEM CELLS, 2013, 31 (12) :2737-2746
[95]   Systemic administration of exosomes released from mesenchymal stromal cells promote functional recovery and neurovascular plasticity after stroke in rats [J].
Xin, Hongqi ;
Li, Yi ;
Cui, Yisheng ;
Yang, James J. ;
Zhang, Zheng Gang ;
Chopp, Michael .
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2013, 33 (11) :1711-1715
[96]   Exosome-Mediated Transfer of miR-133b from Multipotent Mesenchymal Stromal Cells to Neural Cells Contributes to Neurite Outgrowth [J].
Xin, Hongqi ;
Li, Yi ;
Buller, Ben ;
Katakowski, Mark ;
Zhang, Yi ;
Wang, Xinli ;
Shang, Xia ;
Zhang, Zheng Gang ;
Chopp, Michael .
STEM CELLS, 2012, 30 (07) :1556-1564
[97]   Emerging potential of exosomes for treatment of traumatic brain injury [J].
Xiong, Ye ;
Mahmood, Asim ;
Chopp, Michael .
NEURAL REGENERATION RESEARCH, 2017, 12 (01) :19-22
[98]   Investigational agents for treatment of traumatic brain injury [J].
Xiong, Ye ;
Zhang, Yanlu ;
Mahmood, Asim ;
Chopp, Michael .
EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2015, 24 (06) :743-760
[99]   Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells [J].
Xu, Ji-Feng ;
Yang, Guang-hai ;
Pan, Xiao-Hong ;
Zhang, Shui-Jun ;
Zhao, Chen ;
Qiu, Bin-Song ;
Gu, Hai-Feng ;
Hong, Jian-Fei ;
Cao, Li ;
Chen, Yu ;
Xia, Bing ;
Bi, Qin ;
Wang, Ya-Ping .
PLOS ONE, 2014, 9 (12)
[100]  
Xu R, 2017, METHODS MOL BIOL, V1545, P91, DOI 10.1007/978-1-4939-6728-5_7
234567891011