Highly efficient alkylation of epoxides with R3Al/H2O systems based on the double activation of epoxy oxygens

被引：27

作者：

Abe, N

Hanawa, H

Maruoka, K ^{[1
]}

Sasaki, M

Miyashita, M

机构：

[1] Hokkaido Univ, Grad Sch Sci, Organomet Chem Lab, Sapporo, Hokkaido 060, Japan

[2] Hokkaido Univ, Grad Sch Sci, Lab Org Chem 2, Div Chem, Sapporo, Hokkaido 0600810, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 29期

关键词：

D O I：

10.1016/S0040-4039(99)01025-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Alkylation of epoxides can be effected with trialkylaluminum/water system, which is much superior to the parent trialkylalnminum. Bidentate bis(dialkyl)aluminoxanes and their hypothetical analogues seem to be active species for the double activation of epoxy substrates. Such double-activation ability is emphasized using several synthetic examples in comparison with the corresponding monodentate derivatives. The double coordination complex formation of bidentate (Me2Al)(2)O is characterized with THF by H-1 and C-13 NMR spectroscopy. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：5369 / 5372

页数：4

共 10 条

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[2]

Maruoka K, 1999, CHEM-EUR J, V5, P829, DOI 10.1002/(SICI)1521-3765(19990301)5:3<829::AID-CHEM829>3.3.CO

[3]

2-S

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