Synthesis of Blended Fibers of Poly(3-hydroxybutyric acid) and Poly(propylene carbonate) Scaffolds for Tissue Engineering

被引：8

作者：

Nagiah, Naveen ^{[1
]}

Ramanathan, Giriprasath ^{[1
]}

Uma, Tiruchirapalli Sivagnanam ^{[1
]}

Madhavi, Lakshmi ^{[2
]}

Anitha, R. ^{[2
]}

Natarajan, Tirupattur Srinivasan ^{[3
]}

机构：

[1] Cent Leather Res Inst, Bioprod Lab, Madras 600020, Tamil Nadu, India

[2] Cavinkare Res Ctr, Madras, Tamil Nadu, India

[3] Indian Inst Technol, Dept Phys, Conducting Polymer Lab, Madras 600036, Tamil Nadu, India

来源：

ADVANCES IN POLYMER TECHNOLOGY | 2013年 / 32卷 / 04期

关键词：

Bioengineering; Biomaterials; Biomimetic; Electrospinning; Skin regeneration; DEGRADATION;

D O I：

10.1002/adv.21370

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Electrospinning is one of the cheapest and upscalable techniques to mimic the structure of the extracelluar matrix of tissues and organs. Fibers of submicron and nanoscale dimensions were obtained by electrospining blended polymer solutions of poly(3-hydroxybutyric acid) and poly(propylene carbonate) using 1,1,1,3,3,3 hexafluoro-2-propanol and 2,2,2 trifluoroethanol as solvents. The resultant fibers were characterized using scanning electron microscopy, differential scanning calorimetry, and attenuated total reflection-fourier transformed infrared spectroscopy. The fibrous scaffold had competent tensile properties and supported the growth and proliferation of human dermal fibroblasts and keratinocytes with normal morphology, thus proving its reliability in using it as a potential scaffold for skin regeneration. (c) 2013 Wiley Periodicals, Inc. Adv Polym Technol 2013, 32, 21370; View this article online at wileyonlinelibrary.com. DOI 10.1002/adv.21370

引用

页数：5

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