Palladium-Catalyzed Oxalyl Amide Directed Silylation and Germanylation of Amine Derivatives

被引：74
作者：
Chen, Changpeng [1 ]
Guan, Mingyu [1 ]
Zhang, Jingyu [2 ,3 ]
Wen, Zhenkang [4 ]
Zhao, Yingsheng [1 ]
机构：
[1] Soochow Univ, Coll Chem Chem Engn & Mat Sci, Key Lab Organ Synth Jiangsu Prov, Suzhou 215123, Peoples R China
[2] Soochow Univ, China Coll Phys Optoelect & Energy, Suzhou 215006, Peoples R China
[3] Soochow Univ, Collaborat Innovat Ctr Suzhou Nano Sci & Technol, Suzhou 215006, Peoples R China
[4] Shanxi Univ, Coll Chem & Chem Engn, Taiyuan 030006, Peoples R China
来源：
ORGANIC LETTERS | 2015年 / 17卷 / 15期
基金：
中国国家自然科学基金;
关键词：
C-H SILYLATION; CARBON-HYDROGEN BONDS; C(SP(3))-H BONDS; ARENES; HYDROSILANES; C(SP(2))-H; ARYL; ACTIVATION; ASSISTANCE; ARYLATION;
D O I：
10.1021/acs.orglett.5b01393
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Palladium-catalyzed direct ortho-silylation of oxalyl amide-protected phenylmethanamine and phenethylamine with commercially available disilanes is reported. Germanylation products were also produced under the same reaction conditions. This protocol tolerated oxalyl amide-protected aliphatic, amines, which gave gamma-C-H silylation products.
引用
收藏
页码：3646 / 3649
页数：4
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