Palladium-Catalyzed Oxalyl Amide Directed Silylation and Germanylation of Amine Derivatives

被引：77

作者：

Chen, Changpeng ^{[1
]}

Guan, Mingyu ^{[1
]}

Zhang, Jingyu ^{[2
,3
]}

Wen, Zhenkang ^{[4
]}

Zhao, Yingsheng ^{[1
]}

机构：

[1] Soochow Univ, Coll Chem Chem Engn & Mat Sci, Key Lab Organ Synth Jiangsu Prov, Suzhou 215123, Peoples R China

[2] Soochow Univ, China Coll Phys Optoelect & Energy, Suzhou 215006, Peoples R China

[3] Soochow Univ, Collaborat Innovat Ctr Suzhou Nano Sci & Technol, Suzhou 215006, Peoples R China

[4] Shanxi Univ, Coll Chem & Chem Engn, Taiyuan 030006, Peoples R China

来源：

ORGANIC LETTERS | 2015年 / 17卷 / 15期

基金：

中国国家自然科学基金;

关键词：

C-H SILYLATION; CARBON-HYDROGEN BONDS; C(SP(3))-H BONDS; ARENES; HYDROSILANES; C(SP(2))-H; ARYL; ACTIVATION; ASSISTANCE; ARYLATION;

D O I：

10.1021/acs.orglett.5b01393

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium-catalyzed direct ortho-silylation of oxalyl amide-protected phenylmethanamine and phenethylamine with commercially available disilanes is reported. Germanylation products were also produced under the same reaction conditions. This protocol tolerated oxalyl amide-protected aliphatic, amines, which gave gamma-C-H silylation products.

引用

页码：3646 / 3649

页数：4

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