Functionalized graphene nanocomposites for enhancing photothermal therapy in tumor treatment

被引:299
作者
Chen, Yu-Wei [1 ]
Su, Yu-Lin [2 ]
Hu, Shang-Hsiu [2 ]
Chen, San-Yuan [1 ]
机构
[1] Natl Chiao Tung Univ, Dept Mat Sci & Engn, Hsinchu, Taiwan
[2] Natl Tsing Hua Univ, Dept Biomed Engn & Environm Sci, Hsinchu, Taiwan
关键词
Graphene; Photothermal therapy; Composites; Drug delivery; Tumor therapy; UP-CONVERSION NANOPARTICLES; NEAR-INFRARED ABSORBENCY; DRUG-DELIVERY; IN-VITRO; OXIDE NANOSHEETS; NANO-GRAPHENE; GOLD NANORODS; ULTRASOUND-HYPERTHERMIA; PHOTODYNAMIC THERAPY; SONODYNAMIC THERAPY;
D O I
10.1016/j.addr.2016.05.022
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Graphene and its derivatives have unique physical and chemical properties that make them promising vehicles for photothermal therapy (PTT)-based cancer treatment. With intrinsic near-infrared (NIR) absorption properties, graphene-based nanomaterials can be used for PTT and other therapeutics, particularly in combination therapy, to provide successful thermal ablation of cancer cells. In the recent years, advances in graphene-based PTT have produced efficient and efficacious tumor inhibition via nanomaterial structural design and different functionalizations of graphene-derived nanocomposites. Graphene-based nanosystems exhibit multifunctional properties that are useful for PTT applications including enhancement of multimodalities, guided imaging, enhanced chemotherapy and low-power efficient PTT for optimum therapeutic efficiency. Therefore, in this review, we address critical issues and future aspects of PTT-based combination therapy. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码:190 / 204
页数:15
相关论文
共 180 条
[1]   Polyphenols attached graphene nanosheets for high efficiency NIR mediated photodestruction of cancer cells [J].
Abdolahad, M. ;
Janmaleki, M. ;
Mohajerzadeh, S. ;
Akhavan, O. ;
Abbasi, S. .
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2013, 33 (03) :1498-1505
[2]  
Acik M, 2010, NAT MATER, V9, P840, DOI [10.1038/nmat2858, 10.1038/NMAT2858]
[3]   Carbon nanotubes in cancer therapy: a more precise look at the role of carbon nanotube-polymer interactions [J].
Adeli, Mohsen ;
Soleyman, Rouhollah ;
Beiranvand, Zahra ;
Madani, Fahimeh .
CHEMICAL SOCIETY REVIEWS, 2013, 42 (12) :5231-5256
[4]   Dose-dependent effects of nanoscale graphene oxide on reproduction capability of mammals [J].
Akhavan, Omid ;
Ghaderi, Elham ;
Hashemi, Ehsan ;
Akbari, Ebrahim .
CARBON, 2015, 95 :309-317
[5]   Zinc ferrite spinel-graphene in magneto-photothermal therapy of cancer [J].
Akhavan, Omid ;
Meidanchi, Alireza ;
Ghaderi, Elham ;
Khoei, Samideh .
JOURNAL OF MATERIALS CHEMISTRY B, 2014, 2 (21) :3306-3314
[6]   Graphene Nanomesh Promises Extremely Efficient In Vivo Photothermal Therapy [J].
Akhavan, Omid ;
Ghaderi, Elham .
SMALL, 2013, 9 (21) :3593-3601
[7]   Nontoxic concentrations of PEGylated graphene nanoribbons for selective cancer cell imaging and photothermal therapy [J].
Akhavan, Omid ;
Ghaderi, Elham ;
Emamy, Hamed .
JOURNAL OF MATERIALS CHEMISTRY, 2012, 22 (38) :20626-20633
[8]   Size-dependent genotoxicity of graphene nanoplatelets in human stem cells [J].
Akhavan, Omid ;
Ghaderi, Elham ;
Akhavan, Alireza .
BIOMATERIALS, 2012, 33 (32) :8017-8025
[9]   The use of a glucose-reduced graphene oxide suspension for photothermal cancer therapy [J].
Akhavan, Omid ;
Ghaderi, Elham ;
Aghayee, Samira ;
Fereydooni, Yasamin ;
Talebi, Ali .
JOURNAL OF MATERIALS CHEMISTRY, 2012, 22 (27) :13773-13781
[10]   Gold nanorods: Their potential for photothermal therapeutics and drug delivery, tempered by the complexity of their biological interactions [J].
Alkilany, Alaaldin M. ;
Thompson, Lucas B. ;
Boulos, Stefano P. ;
Sisco, Patrick N. ;
Murphy, Catherine J. .
ADVANCED DRUG DELIVERY REVIEWS, 2012, 64 (02) :190-199