Occurrence and fate of antibiotics and antibiotic resistance genes in typical urban water of Beijing, China

被引：225

作者：

Liu, Xiaohui ^{[1
,2
]}

Zhang, Guodong ^{[3
]}

Liu, Ying ^{[1
]}

Lu, Shaoyong ^{[1
]}

Qin, Pan ^{[1
]}

Guo, Xiaochun ^{[1
]}

Bi, Bin ^{[1
]}

Wang, Lei ^{[1
]}

Xi, Beidou ^{[1
]}

Wu, Fengchang ^{[1
]}

Wang, Weiliang ^{[3
]}

Zhang, Tingting ^{[4
]}

机构：

[1] Chinese Res Inst Environm Sci, SEPSORSLD, Natl Engn Lab Lake Pollut Control & Ecol Restorat, State Key Lab Environm Criteria Risk Assessment,R, Beijing 100012, Peoples R China

[2] Tsinghua Univ, Sch Environm, Beijing 100084, Peoples R China

[3] Shandong Normal Univ, Sch Geog & Environm, Jinan 250358, Shandong, Peoples R China

[4] Beijing Univ Chem Technol, Sch Chem Engn, Beijing 100029, Peoples R China

来源：

ENVIRONMENTAL POLLUTION | 2019年 / 246卷

基金：

中国国家自然科学基金;

关键词：

Antibiotics; ARGs; Occurrence; Typical urban water; SEWAGE-TREATMENT PLANTS; MUNICIPAL WASTE-WATER; VETERINARY ANTIBIOTICS; RISK-ASSESSMENT; SURFACE-WATER; AQUATIC ENVIRONMENTS; BACTERIAL COMMUNITY; DONGTING LAKE; HAIHE RIVER; PHARMACEUTICALS;

D O I：

10.1016/j.envpol.2018.12.005

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The pollution of antibiotics and antibiotic resistance genes (ARGs) has been highlighted on a global scale because of their serious threats to the environment and human health. Typical urban water in cities with high population density are ideal mediums for the acquisition and spread of antibiotics and ARGs. The pollution level of a broad range of antibiotics and ARGs in hospital wastewater, groundwater and the Wenyu River, and their fates through three sewage treatment plants (STPs) were investigated in this study. The concentrations of the 11 detected antibiotics ranged from not detected (ND)-16800 ng L-1 in diverse water samples from Beijing, and fluoroquinolones were detected at the highest concentration, especially in the hospital samples. The maximum concentrations of antibiotics in STPs and hospital were 1-3 orders of magnitude higher than those in the surface water from Wenyu River and groundwater. Good removal efficiencies by treatment processes were observed for tetracyclines and quinolones, and low removal efficiencies were observed for sulfonamides and macrolides. These results also revealed that the sulfonamide resistance genes (sull, sul2) and macrolide resistance genes (ermB) were detected at the highest relative abundances (7.11 x 10(-2)-1.18 x 10(-1)) in the water bodies of Beijing. It was worth noting that sull abundance was the highest in groundwater samples. The relative abundance of most ARGs in STPs exhibited a declining trend in the order of influent > secondary effluents > effluent. However, the relative abundance of sul 1, sul 2 and tetC in the effluent was higher than those in the influent. The incomplete removal of antibiotics and ARGs in STPs poses a serious threat to the receiving rivers, and affects ecosystem security. Overall, our findings provide favorable support for a further investigation of the spread and risk of antibiotics and ARGs from diverse sources (e.g., STPs and hospitals) to the aquatic environment. (C) 2018 Elsevier Ltd. All rights reserved.

引用

页码：163 / 173

页数：11

共 85 条

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