The mitochondrial transcriptome of the anglerfishLophius piscatorius

被引：7

作者：

Dubin, Arseny ^{[1
]}

Jorgensen, Tor Erik ^{[1
]}

Jakt, Lars Martin ^{[1
]}

Johansen, Steinar Daae ^{[1
]}

机构：

[1] Nord Univ, Fac Biosci & Aquaculture, Genom Grp, N-8049 Bodo, Norway

来源：

BMC RESEARCH NOTES | 2019年 / 12卷 / 01期

关键词：

Anglerfish; Antisense RNA; Humanin; Mitogenome; Long noncoding RNA; lncCOI; mtDNA; NONCODING RNAS; ATLANTIC COD; HUMANIN; APOPTOSIS; FEATURES; GENOME;

D O I：

10.1186/s13104-019-4835-6

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Objective Analyze key features of the anglerfishLophius piscatoriusmitochondrial transcriptome based on high-throughput total RNA sequencing. Results We determined the complete mitochondrial DNA and corresponding transcriptome sequences ofL. piscatorius. Key features include highly abundant mitochondrial ribosomal RNAs (10-100 times that of mRNAs), and that cytochrome oxidase mRNAs appeared > 5 times more abundant than both NADH dehydrogenase and ATPase mRNAs. Unusual for a vertebrate mitochondrial mRNA, the polyadenylated COI mRNA was found to harbor a 75 nucleotide 3 ' untranslated region. The mitochondrial genome expressed several non-canonical genes, including the long noncoding RNAs lncCR-H, lncCR-L and lncCOI. Whereas lncCR-H and lncCR-L mapped to opposite strands in a non-overlapping organization within the control region, lncCOI appeared novel among vertebrates. We found lncCOI to be a highly abundant mitochondrial RNA in antisense to the COI mRNA. Finally, we present the coding potential of a humanin-like peptide within the large subunit ribosomal RNA.

引用

页数：7

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