Construction of β-haloenamides via direct copper-promoted coupling of lactams with 2-chloro and 2-bromo vinyliodides

被引：52

作者：

Sun, CX ^{[1
]}

Camp, JE ^{[1
]}

Weinreb, SM ^{[1
]}

机构：

[1] Penn State Univ, Dept Chem, University Pk, PA 16802 USA

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 09期

关键词：

D O I：

10.1021/ol060093a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cu(I)-catalyzed coupling of lactams with (E)-2-chlorovinyliodides or (E)-2-bromovinyliodides produces the corresponding beta-haloenamides in moderate to excellent yields.

引用

页码：1779 / 1781

页数：3

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