Multiple functions of the integrin α6β4 in epidermal homeostasis and tumorigenesis

被引：106
作者：
Wilhelmsen, K [1 ]
Litjens, SHM [1 ]
Sonnenberg, A [1 ]
机构：
[1] Netherlands Canc Inst, Div Cell Biol, NL-1066 CX Amsterdam, Netherlands
来源：
MOLECULAR AND CELLULAR BIOLOGY | 2006年 / 26卷 / 08期
关键词：
D O I：
10.1128/MCB.26.8.2877-2886.2006
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：2877 / 2886
页数：10
相关论文
共 102 条
[1]   Targeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle, and heart cytoarchitecture [J].
Andra, K ;
Lassmann, H ;
Bittner, R ;
Shorny, S ;
Fassler, R ;
Propst, F ;
Wiche, G .
GENES & DEVELOPMENT, 1997, 11 (23) :3143-3156
[2]   p53 inhibits α6β4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB [J].
Bachelder, RE ;
Ribick, MJ ;
Marchetti, A ;
Falcioni, R ;
Soddu, S ;
Davis, KR ;
Mercurio, AM .
JOURNAL OF CELL BIOLOGY, 1999, 147 (05) :1063-1072
[3]   β4 integrin is a transforming molecule that unleashes met tyrosine kinase tumorigenesis [J].
Bertotti, A ;
Comoglio, PM ;
Trusolino, L .
CANCER RESEARCH, 2005, 65 (23) :10674-10679
[4]   EPILIGRIN, A NEW CELL-ADHESION LIGAND FOR INTEGRIN ALPHA-3-BETA-1 IN EPITHELIAL BASEMENT-MEMBRANES [J].
CARTER, WG ;
RYAN, MC ;
GAHR, PJ .
CELL, 1991, 65 (04) :599-610
[5]   Integrin α6β4 promotes expression of autotaxin/ENPP2 autocrine motility factor in breast carcinoma cells [J].
Chen, M ;
O'Connor, KL .
ONCOGENE, 2005, 24 (32) :5125-5130
[6]   Integrin α3β1 directs the stabilization of a polarized lamellipodium in epithelial cells through activation of Rac1 [J].
Choma, DP ;
Pumiglia, K ;
DiPersio, CM .
JOURNAL OF CELL SCIENCE, 2004, 117 (17) :3947-3959
[7]   The met receptor and α6β4 integrin can function independently to promote carcinoma invasion [J].
Chung, J ;
Yoon, SO ;
Lipscomb, EA ;
Mercurio, AM .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (31) :32287-32293
[8]   Integrin (α6β4) regulation of eIF-4E activity and VEGF translation:: a survival mechanism for carcinoma cells [J].
Chung, J ;
Bachelder, RE ;
Lipscomb, EA ;
Shaw, LM ;
Mercurio, AM .
JOURNAL OF CELL BIOLOGY, 2002, 158 (01) :165-174
[9]   ACTIVATION OF THE P21 PATHWAY OF GROWTH ARREST AND APOPTOSIS BY THE BETA(4) INTEGRIN CYTOPLASMIC DOMAIN [J].
CLARKE, AS ;
LOTZ, MM ;
CHAO, C ;
MERCURIO, AM .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (39) :22673-22676
[10]   CD 151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin [J].
Crew, VK ;
Burton, N ;
Kagan, A ;
Green, CA ;
Levene, C ;
Flinter, F ;
Brady, RL ;
Daniels, G ;
Anstee, DJ .
BLOOD, 2004, 104 (08) :2217-2223
12345678910