Dual-Channel Electrospray Microchip

被引：8
|
作者：
Lu, Yu [1 ]
Liu, Fang [1 ]
Lion, Niels [2 ]
Girault, Hubert H. [1 ]
机构：
[1] Ecole Polytech Fed Lausanne, Stn 6, Lab Electrochim Phys & Analyt, CH-1015 Lausanne, Switzerland
[2] Serv Reg Vaudois Transfus Sanguine, Epalinges, Switzerland
来源：
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY | 2013年 / 24卷 / 03期
基金：
瑞士国家科学基金会;
关键词：
Dual-channel emitter; Microchip; Micro-electrospray ionization; Mass spectrometry; MASS-SPECTROMETRY; IONIZATION;
D O I：
10.1007/s13361-012-0547-z
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A dual-channel electrospray microchip has been developed for electrospray ionization mass spectrometry (ESI-MS) where aqueous samples are mixed at the Taylor cone with an organic buffer. Due to the fast and effective mixing in the Taylor cone, the aqueous sample can be well ionized with a high ion intensity. The influence of geometric parameters such as the distance between the two microchannels at their junction at the tip of the emitter has been investigated together with chemical parameters such as the organic buffer composition.
引用
收藏
页码：454 / 457
页数：4
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