The contribution of nuclear compartmentalization to gene regulation

被引：165
作者：
Carmo-Fonseca, M [1 ]
机构：
[1] Univ Lisbon, Fac Med, Inst Mol Med, P-1649028 Lisbon, Portugal
来源：
CELL | 2002年 / 108卷 / 04期
关键词：
D O I：
10.1016/S0092-8674(02)00650-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Recent developments in live-cell imaging are challenging our stereotyped view of the fixed cell nucleus. The emerging picture is that nuclear processes may rely on a constant flow of molecules between dynamic compartments created by relatively immobile binding or assembly sites. This article discusses current views on the origins of nuclear compartments and their roles in gene expression.
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收藏
页码：513 / 521
页数：9
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