Genetic studies of IgA nephropathy

被引:11
作者
Maxwell, PH
Wang, YM
机构
[1] Univ London Imperial Coll Sci Technol & Med, Hammersmith Hosp, Renal Sect, London, England
[2] Zhongshan Med Coll, Dept Med Genet, Guangzhou, Peoples R China
来源
NEPHRON EXPERIMENTAL NEPHROLOGY | 2006年 / 102卷 / 3-4期
关键词
IgA nephropathy; glomerulonephritis; genetics;
D O I
10.1159/000089685
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
IgA nephropathy is the commonest form of glomerulonephritis worldwide, but we still know relatively little about its pathogenesis. Potentially, genetic studies might provide new insights and suggest novel therapeutic approaches to this important cause of chronic kidney disease. Two approaches that are likely to yield new information are analysis of multiply affected pedigrees and large-scale, well-controlled association studies. Copyright (c) 2006 S. Karger AG, Basel.
引用
收藏
页码:E76 / E80
页数:5
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